Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Udaiyappan Janakiraman"'
Autor:
Chinnasamy Dhanalakshmi, Udaiyappan Janakiraman, Mark A. Nelson, Aubin Moutal, Rajesh Khanna, Kohji Fukunaga
Publikováno v:
Neurobiology of disease
Neurobiology of Disease, Vol 149, Iss, Pp 105224-(2021)
Neurobiology of Disease, Vol 149, Iss, Pp 105224-(2021)
The TATA-box binding protein associated factor 1 (TAF1) is part of the TFIID complex that plays a key role during the initiation of transcription. Variants of TAF1 are associated with neurodevelopmental disorders. Previously, we found that CRISPR/Cas
Autor:
Shelby N. Batchelor, Mark A. Nelson, Udaiyappan Janakiraman, Annaduri Anandhan, Lisa Boinon, Jie Yu, Aubin Moutal, Rajesh Khanna, Dhanalakshmi Chinnasamy
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 132, Iss, Pp-(2019)
Neurobiology of Disease, Vol 132, Iss, Pp-(2019)
TAF1/MRSX33 intellectual disability syndrome is an X-linked disorder caused by loss-of-function mutations in the TAF1 gene. How these mutations cause dysmorphology, hypotonia, intellectual and motor defects is unknown. Mouse models which have embryon