Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Winfred C Wang"'
Autor:
Ashok Srinivasan, Aditya H. Gaur, Randall T. Hayden, Wing Leung, Zhengming Gu, Teresa Smith, Winfred C. Wang, Guolian Kang
Publikováno v:
Pediatric Blood & Cancer
Human rhinovirus (HRV), human coronavirus (hCoV), human bocavirus (hBoV), and human metapneumovirus (hMPV) infections in children with sickle cell disease have not been well studied.Nasopharyngeal wash specimens were prospectively collected from 60 c
Autor:
Nicholas S Whipple, Winfred C. Wang, Kerri Nottage, JoAnn M Moulds, Dawn A B Moreau, Jane S. Hankins
Publikováno v:
Pediatric Blood & Cancer. 62:2044-2046
Paroxysmal cold hemoglobinuria (PCH) is an autoimmune hemolytic anemia (AIHA) characterized by the presence of a Donath–Landsteiner (D-L) antibody. PCH occurs most commonly in young children and is associated with acute, often self-limited hemolyti
Autor:
Mary Ellen Hoehn, Matthew P. Smeltzer, Banu Aygun, Jeremie H. Estepp, Winfred C. Wang, Jane S. Hankins
Publikováno v:
British Journal of Haematology. 161:402-405
Elevated foetal haemoglobin (HbF) levels are protective against some manifestations of sickle cell anaemia but the impact on retinopathy is unknown. We report on 123 children with HbSS, 10.6% of whom developed retinopathy. Independent of hydroxycarba
Autor:
Patrick Kelly, Carlos Rodriguez-Galindo, Gerald G. Presbury, Michael Jeng, Martha Rieman, Winfred C. Wang
Publikováno v:
American Journal of Hematology. 69:179-184
Langerhans cell histiocytosis (LCH) is a disorder characterized by proliferation of activated Langerhans cells. Immune dysregulation is believed to be part of the pathogenesis. Although current therapies are very effective at inducing remission, mult
Autor:
Winfred C. Wang, Laura C. Bowman, Ely Benaim, John M. Cunningham, N Pitts, Edwin M. Horwitz, Paul Woodard
Publikováno v:
Bone Marrow Transplantation. 27:589-592
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disease of hematopoiesis due to a mutation in the PIG-A gene. Affected patients may demonstrate hemolysis or venous thrombosis, and may develop MDS or aplastic anemia. Successful results
Publikováno v:
British Journal of Haematology. 109:322-327
The adhesion of sickle erythrocytes to the vascular endothelium and subendothelial matrix probably contributes to the pathogenesis of vaso-occlusive disease. The chemotherapeutic agent hydroxyurea (HU) decreases the frequency of vaso-occlusive crises
Autor:
Sheldon B. Korones, Rhonda Dancy, Winfred C. Wang, Judith A. Wilimas, F. Ann Hayes, Lakshmi Venkateswaran, Jane Hayden
Publikováno v:
Pediatric Hematology and Oncology. 17:469-473
To evaluate the efficacy of granulocyte-macrophage colony-stimulating factor (GM-CSF) in improving neutrophil counts and survival of neutropenic septic neonates, the authors studied 8 neonates with gestational or postconceptional age at least 30 week
Autor:
Vivien A. Sheehan, Jonathan M. Flanagan, Abdullah Kutlar, Winfred C. Wang, Thad A. Howard, Bruce W. Thompson, Russell E. Ware, Zhaoyu Luo
Publikováno v:
American journal of hematology. 88(7)
The recently completed BABY HUG trial investigated the safety and efficacy of hydroxyurea in infants with sickle cell anemia (SCA). To investigate the effects of known genetic modifiers, genomic DNA on 190 randomized subjects were analyzed for alpha
Autor:
George R. Buchanan, John M. Falletta, Clarice D. Reid, David L. Becton, Rathi V. Iyer, Neil J. Grossman, Ann B. Bjornson, Winfred C. Wang, Karen Kalinyak, Elliott Vichinsky, Gerald M. Woods, Helen S. Johnstone, Michael R. DeBaun, Joel Verter, C. Tate Holbrook, Doris L. Wethers, Gregory H. Reaman, Thomas R. Kinney, Charles H. Pegelow, Scott T. Miller
Publikováno v:
The Journal of Pediatrics. 129:828-835
OBJECTIVES: (1) To determine serotype-specific IgG antibody responses to reimmunization with pneumococcal polysaccharide vaccine at age 5 years in children with sickle cell anemia and (2) to determine whether continued penicillin prophylaxis had any
Autor:
Marilyn J. Telen, Kim Smith-Whitley, Samir K. Ballas, Cage S. Johnson, Carolyn Hoppe, Winfred C. Wang, Susan Lieff, Carlton Dampier, Zora R. Rogers, Matthew M. Heeney, Lennette Benjamin
Publikováno v:
American Journal of Hematology.
Sickle cell disease (SCD) is a pleiotropic genetic disorder of hemoglobin that has profound multiorgan effects. The low prevalence of SCD ( approximately 100,000/US) has limited progress in clinical, basic, and translational research. Lack of a large