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Autor:
Natálie Klubíčková, Michael Michal, Abbas Agaimy, Nina Zidar, Michal Pavlovský, Kenji Yorita, Petr Grossmann, Veronika Hájková, Nikola Ptáková, Petr Šteiner, Michal Michal
Publikováno v:
Virchows Archiv. 481:721-729
We report 7 cases of an indolent, variably myxoid tumor of the vocal cords, characterized by overt cellular atypia with large cells containing intranuclear and intracytoplasmic vacuoles, delicate curvilinear vessels, and sparse inflammatory infiltrat
Publikováno v:
Virchows Archiv. 481(2):307-312
The diagnosis of mesothelioma in situ (MIS) is challenging with conventional diagnostic approaches. Although recent advances in genomic-based assays have made it possible to diagnose MIS, the prognosis, treatment indications, and prognostic factors r
Autor:
Maurizio Colecchia, Biagio Paolini, Giacomo Maria Pini, Laura Carpenito, Beatrice Maghini, Barbara Avuzzi, Anna Maria Paganoni, Nicola Nicolai
Publikováno v:
Virchows Archiv. 481:695-701
Pure seminomas represent the majority of testicular germ cell tumors and accurate diagnosis and staging require an accurate sampling of radical orchiectomy specimens. The aim of our study is to find the most informative gross sampling method for orch
Autor:
Masahito Watanabe, Kazuhiro Umeyama, Kazuaki Nakano, Hitomi Matsunari, Toru Fukuda, Kei Matsumoto, Susumu Tajiri, Shuichiro Yamanaka, Koki Hasegawa, Kazutoshi Okamoto, Ayuko Uchikura, Shuko Takayanagi, Masaki Nagaya, Takashi Yokoo, Hiromitsu Nakauchi, Hiroshi Nagashima
Publikováno v:
Laboratory Investigation. 102:560-569
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, manifesting as the progressive development of fluid-filled renal cysts. In approximately half of all patients with ADPKD, end-stage renal disease result
Autor:
Jia-hao Bao, Jiang-bo Li, Han-sen Lin, Wen-jin Zhang, Bing-yan Guo, Jun-jie Li, Liang-min Fu, Yang-peng Sun
Publikováno v:
Analytical Cellular Pathology. 2022:1-27
Clear cell renal cell carcinoma (ccRCC) is the most common histological and devastating subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes prominent inflammatory responses. miRNAs play a significant role in ca
Autor:
Shi Liang, Haoda Lu, Min Zang, Xiangxue Wang, Yiping Jiao, Tingting Zhao, Eugene Yujun Xu, Jun Xu
Publikováno v:
Cytometry Part A. 101:658-674
The development of mouse spermatozoa is a continuous process from spermatogonia, spermatocytes, spermatids to mature sperm. Those developing germ cells (spermatogonia, spermatocyte, and spermatids) together with supporting sertoli cells are all enclo
Publikováno v:
Virchows Archiv. 481:511-516
We report a case of primary rectal neoplasm with a novel DDX5-TFEB fusion in a 14-year-old boy. Histologically, the neoplasm was composed of epithelioid tumor cells with abundant clear to eosinophilic cytoplasm, arranged in nests with rich stromal ca
Publikováno v:
Laboratory Investigation. 102:332-340
Prostate cancer is the most common cancer among men and has a high incidence and associated mortality worldwide. It is an androgen-driven disease in which tumor growth is triggered via ligand-mediated signaling through the androgen receptor (AR). Rec
Autor:
Tianqing Ding, Jing Yan, Wencai Li, Li Wang, Xiangxiang Wang, Jingliang Cheng, Dongling Pei, Weiwei Wang, Wenchao Duan, Zhen Liu, Xuanke Hong, Zhicheng Li, Zhen-Yu Zhang, Qiuchang Sun, Xianzhi Liu, Chen Sun, Wenqing Wang, Shenghai Zhang, Yu Guo
Publikováno v:
Laboratory Investigation. 102:154-159
Determination of 1p/19q co-deletion status is important for the classification, prognostication, and personalized therapy in diffuse lower-grade gliomas (LGG). We developed and validated a deep learning imaging signature (DLIS) from preoperative magn
Autor:
Hongseok Yun, Seung Hong Choi, Ka Young Lim, Seung-Ki Kim, Yumi Shim, Tae Min Kim, Jin-Woo Park, Hyunhee Kim, Jeongwan Kang, Sung Hye Park, Chul-Kee Park, Kwanghoon Lee, Jae Kyung Won
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations. Here, we report 13 MMRD-associated (9 sporadic and 4 Lynch syndrome) primary brain tumors to determine clinicopath