Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ena Wang"'
Autor:
Craig L. Slingluff, Yongde Bao, Donna H. Deacon, Walter C. Olson, Ileana S. Mauldin, Ena Wang
Publikováno v:
International Journal of Cancer. 137:1386-1396
Clinical approaches to treat advanced melanoma include immune therapies, whose benefits depend on tumor-reactive T-cell infiltration of metastases. However, most tumors lack significant immune infiltration prior to therapy. Selected chemokines promot
Autor:
José Medina-Echeverz, Michael P. Manns, Jonathan M. Weiss, Veena Kapoor, Jay A. Berzofsky, Francesco M. Marincola, Robert H. Wiltrout, Jaba Gamrekelashvili, Nga V. Hawk, Firouzeh Korangy, Ena Wang, Tamar Kapanadze, Masaki Terabe, Tim F. Greten
Publikováno v:
European Journal of Immunology. 45:1148-1158
Immunosuppressive CD11b(+) Gr-1(+) myeloid-derived suppressor cells (MDSCs) accumulate in the livers of tumor-bearing (TB) mice. We studied hepatic MDSCs in two murine models of immune-mediated hepatitis. Unexpectedly, treatment of TB mice with Conca
Autor:
M K Al-Kowari, Dhanya Kizhakayil, Lotfi Chouchane, A Haoudi, A Ismail Chouchane, Pu Li, George Kulik, Ena Wang, M A Al-Muftah, Konduru S Sastry, Francesco M. Marincola
Publikováno v:
Cell Death & Differentiation. 21:1936-1949
Emerging evidence suggests that the resistance of cancer stem cells (CSC) to many conventional therapies is one of the major limiting factors of cancer therapy efficacy. Identification of mechanisms responsible for survival and self-renewal of CSC wi
Autor:
Fang Yin, Sawa Ito, Francesco M. Marincola, Alexandros Spyridonidis, Ena Wang, Sid P. Kerkar, Dhanalakshmi Chinnasamy, Pawel Muranski, Gerrit Weber, J. Joseph Melenhorst, Nancy F. Hensel, Neima Hadi, Austin John Barrett
Publikováno v:
Immunology. 143:96-108
A growing body of evidence suggests that inflammatory cytokines have a dualistic role in immunity. In this study, we sought to determine the direct effects of interferon-γ (IFN-γ) on the differentiation and maturation of human peripheral blood mono
Autor:
Hayato Takahashi, Davide Bedognetti, Kazuhiko Igarashi, Kambiz Mousavi, Yuka Kanno, Vittorio Sartorelli, David Clever, Mahadev Rao, Golnaz Vahedi, Kiyoshi Hirahara, Juan Rivera, Francesco M. Marincola, Atsushi Nakamura, Akihiko Muto, Hossein Zare, Rahul Roychoudhuri, Joseph G. Crompton, George A. Punkosdy, Christopher A. Klebanoff, Michael Bonelli, John J. O'Shea, Ena Wang, Hui Liu, Giuseppe Sciumè, Zhiya Yu, Pawel Muranski, Luca Gattinoni, Nicholas P. Restifo, Victoria Hoffmann, Barbara Dema
Publikováno v:
Nature
Diverse autoimmune and allergic diseases are associated with polymorphisms in a locus encoding the transcription factor BACH2; here, BACH2 is shown to be a broad regulator of immune activation that stabilizes the differentiation of Treg cells by repr
Autor:
James W. K. Shih, Harvey J. Alter, Lumin Zhang, Richard Y. Wang, Francesco M. Marincola, Haiping Wang, Ena Wang, Shuaizheng Jia
Publikováno v:
Virology. 438(1):28-36
Protein kinase R (PKR), a sensor of double-stranded RNA, plays an important role in the host response to viral infection. Hepatitis C genotype 2a virus (HCV2a) has been shown to induce PKR activation to suppress the translation of antiviral interfero
Autor:
Luigi Buonaguro, David F. Stroncek, Ena Wang, George K. Lewis, Francesco M. Marincola, Alessandro Monaco, Zoltan Pos, Maria Lina Tornesello, Franco M. Buonaguro, Marianna Sabatino
Publikováno v:
FEBS Letters. 583:3004-3008
The global transcriptional profile of peripheral blood mononuclear cells (PBMCs) stimulated with HIV candidate vaccine (virus-like particles, VLPs) has been evaluated in HIV-infected patients with low/high viral load compared to healthy volunteers. B
Autor:
Shira Perl, Angelique Biancotto, J. Christopher Fuchs, Marc Langweiler, Abigail Wank, Wendell Cook, Ena Wang, Pradeep K. Dagur, J. Philip McCoy, Matthew J. Olnes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
Background Cytokines are humoral molecules that elicit regulatory function in immunologic pathways. The level and type of cytokine production has become critical in distinguishing physiologic from pathologic immune conditions. Cytokine profiling has
Autor:
Richard L. White, David F. Stroncek, Ramy Moharram, Monica C. Panelli, Ena Wang, Brian M. Martin, Leonardo Rossi, Francesco M. Marincola, Mareva Foster, Glen L. Hortin
Publikováno v:
Proteomics. 6(2)
Systemic interleukin-2 (IL-2) administration induces an assortment of downstream effects whose biological and therapeutic significance remains unexplored mostly because of the methodological inability to globally address their complexity. Protein arr
Autor:
Ena Wang
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 3, Iss 1, p 28 (2005)
Journal of Translational Medicine, Vol 3, Iss 1, p 28 (2005)
The study of clinical samples is often limited by the amount of material available to study. While proteins cannot be multiplied in their natural form, DNA and RNA can be amplified from small specimens and used for high-throughput analyses. Therefore