Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Francesco Amenta"'
Publikováno v:
European Journal of Pharmacology
The novel coronavirus, later identified as SARS-CoV-2, originating from Wuhan in China in November 2019, quickly spread around the world becoming a pandemic. Despite the knowledge of previous coronaviruses, such as those responsible for the SARS and
Autor:
Francesco Amenta, Gabriella Marucci, Catia Lambertucci, Michela Buccioni, Diego Dal Ben, Rosaria Volpini
Publikováno v:
Neuropharmacology. 190
Alzheimer's disease (AD), the most common cause of adult-onset dementia is characterized by a progressive decline of cognitive functions accompanied by behavioral manifestations. The main class of drugs currently used for the treatment of AD are acet
Autor:
Rosanna Avola, Giuseppina Raciti, Daniele Tomassoni, S. Grasso, Agatina Campisi, Vincenzo Bramanti, Enea Traini, Francesco Amenta, G. Li Volti, M. Viola
Publikováno v:
Journal of Neuroscience Research. 93:521-529
Astrocyte activity may be modulated by steroid hormones and GFs. This study investigates the interaction between glucocorticoids or estrogens and GFs on the expression of heme oxygenase-1 (HO-1) and cyclin D1 in astrocyte cultures at 14 days treated
Autor:
Laura Serafina Cerasa, Daniele Tomassoni, Piera Sozio, Francesco Amenta, Seyed Khosrow Tayebati, Antonio Di Stefano
Publikováno v:
Journal of the Neurological Sciences. 302:49-57
The influence of one week treatment with the choline-containing phospholipids cytidine-5'-diphosphocholine (CDP-choline) and choline alphoscerate (L-alpha-glyceryl-phosphorylcholine) at choline-equivalent doses (CDP-choline: 325 mg/kg/day; choline al
Autor:
Daniele Tomassoni, Enea Traini, Francesco Amenta, Fiorenzo Mignini, Giorgio Silvestrelli, Alessia Lanari
Publikováno v:
Journal of the Neurological Sciences. 283:219-223
Nicardipine is a dihydropyridine-type Ca(2+) channel blocker (CCB) with strong antihypertensive activity and with a peculiar cerebrovascular profile. This paper has reviewed the main controlled clinical studies on nicardipine in pathologies associate
Publikováno v:
Clinical and Experimental Hypertension. 30:808-826
Control of blood pressure protects against the development of cerebrovascular lesions, stroke, and vascular dementia (VaD). Cerebrovascular disease is increasingly recognized as a cause of cognitive impairment and dementia primarily in the elderly. N
Publikováno v:
Clinical and Experimental Hypertension. 30:95-108
Lovastatin is a lipid-lowering agent indicated for primary hypercholesterolemia. This study has assessed single-dosing pharmacokinetics of lovastatin and of its main metabolite, lovastatin beta-hydroxyacid, and has compared the pharmacokinetics of tw
Publikováno v:
Clinical and Experimental Hypertension. 30:732-743
The cholinergic marker vesicular acetylcholine transporter (VAChT) was investigated in different cerebral areas of spontaneously hypertensive rats (SHR) by immunochemistry (Western blot analysis) and by immunohistochemistry. SHR were used as an anima
Publikováno v:
Clinical and Experimental Hypertension. 29:539-552
Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension. Amlodipine maleate is another salt that is considered, in terms of pharmacokinetics and pharmacodynamics, similar to amlodipine
Publikováno v:
Mechanisms of Ageing and Development. 127:158-165
Behavioural and psychological symptoms of dementia (BPSD) occur in 50-90% of Alzheimer's disease (AD) patients. Imbalance of different neurotransmitters (acetylcholine, dopamine, noradrenaline and serotonin), involvement of specific brain regions res