Zobrazeno 1 - 10
of 110 261
pro vyhledávání: ''
Publikováno v:
Developmental Biology. 498:35-48
Fibroblasts play an important role in maintaining tissue integrity by secreting components of the extracellular matrix and initiating response to injury. Although the function of fibroblasts has been extensively studied in adults, the embryonic origi
Autor:
Jane C Fenelon, Alistair R. Evans, Michael Pyne, Stephen D. Johnston, Neal Anthwal, Abigail S. Tucker, Abbie Bennetts, Marilyn B. Renfree
Publikováno v:
Developmental Biology. 495:8-18
In the short-beaked echidna, Tachyglossus aculeatus, after an initial period of in utero development, the egg is laid in the pouch and incubated for 10 days. During this time, the fetuses develop an egg tooth and caruncle to help them hatch. However,
Publikováno v:
Differentiation. 125:35-44
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung disease that is characterized by enhanced changes in stem cell differentiation and fibroblast proliferation. Lung resident mesenchymal stem cells (LR-MSCs) are im
Autor:
Samuel Long, Brian Berkemeier
Publikováno v:
Methods. 201:49-64
Sensitive detection of viral nucleic acids is critically important for diagnosis and monitoring of the progression of infectious diseases such as those caused by SARS-CoV2, HIV-1, and other viruses. In HIV-1 infection cases, assessing the efficacy of
Autor:
Marion Marchand, Jérémie Teillon, Stéphane Germain, Claudia Umana-Diaz, Florence Ruggiero, Corinne Ardidie-Robouant, Marilyne Malbouyres, Christophe Guilluy, A. Barret, Catherine Monnot, Laurent Muller, Romain Salza, Sylvie Ricard-Blum, Yoann Atlas, Cathy Pichol-Thievend, Philippe Girard
Publikováno v:
Matrix Biology
Matrix Biology, 2023, 88, pp.33-52. ⟨10.1016/j.matbio.2019.11.003⟩
Matrix Biology, 2023, 88, pp.33-52. ⟨10.1016/j.matbio.2019.11.003⟩
International audience; Lysyl oxidases are major actors of microenvironment and extracellular matrix (ECM) remodeling. These cross-linking enzymes are thus involved in many aspects of physiopathology, including tumor progression, fibrosis and cardiov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14f0be8bc5a3b088af8e2d6c98fd4df
https://hal.science/hal-04029951
https://hal.science/hal-04029951
Autor:
Peter Loskill, Tengku Ibrahim Maulana, Adrian Weghofer, Max Urbanczyk, Peter D. Jones, Kathrin Stadelmann, Katja Schenke-Layland
Publikováno v:
Acta Biomaterialia. 140:364-378
Calcified aortic valve disease (CAVD) is the most prevalent valve disease in the elderly. Targeted pharmacological therapies are limited since the underlying mechanisms of CAVD are not well understood. Appropriate 3D in vitro models could potentially
Autor:
Satoshi Matsuoka, Yukari Takeda
Publikováno v:
Journal of Molecular and Cellular Cardiology. 164:42-50
Roles of mitochondria in sinoatrial nodal cells (SANCs) have not been fully clarified. We have previously demonstrated that mitochondrial Ca2+ efflux through the Na+-Ca2+ exchanger, NCXm, modulates sarcoplasmic reticulum (SR) Ca2+ content and automat
Autor:
Shuang Chen, Xiong Gan, Xiuyun Xu, Ming Zhang, Cheng Wang, Yong Bao, Demeng Chen, Jiaxiang Xie, Jingting Li, Kang Li
Publikováno v:
Journal of Genetics and Genomics. 49:230-239
Radiotherapy for head and neck cancer can cause serious side effects, including severe damage to the salivary glands, resulting in symptoms such as xerostomia, dental caries, and oral infection. Due to the lack of long-term treatment for the symptoms
Autor:
Yuji Miyahara, Momoko Sakata, Kazuhiko Ishihara, Fanlu Meng, Hiroaki Hatano, Tatsuro Goda, Akira Matsumoto
Publikováno v:
Acta Biomaterialia. 140:674-685
Epithelial barriers that seal cell gaps by forming tight junctions to prevent the free permeation of nutrients, electrolytes, and drugs, are essential for maintaining homeostasis in multicellular organisms. The development of nanocarriers that can pe
Autor:
Yuka Yoshinouchi, Yukiko Sorayama, Shiro Kitano, Michiya Matsusaki, Shinji Irie, Yasuyuki Naito, Hiroshi Kohara
Publikováno v:
Acta Biomaterialia. 140:275-288
In vitro Construction of the liver sinusoidal structure using artificial tissue is an important but worthwhile challenge, particularly for assessing the risk of diseases such as sinusoidal obstruction syndrome (SOS). Current models are unsuitable for