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Publikováno v:
Internal Medicine Journal. 52:1733-1740
Background Peripherally inserted central catheters (PICCs) are commonly used in cancer patients. PICC-associated upper limb venous thromboembolism (PaULVTE, non-deep and deep involving veins proximal to the brachial vein) and distant VTE (i.e. pulmon
Autor:
Mary Lynn Savoie, Jan Storek, Megan Kinzel, Mona Shafey, Rehan M. Faridi, Faisal Khan, Rutvij A. Khanolkar, Kareem Jamani
Publikováno v:
Cytotherapy. 24:413-420
Background aims The internal tandem duplication of FLT3 (FLT3ITD) and NPM1 mutations (NPM1mut) are well-established prognostic factors in cytogenetically intermediate-risk acute myeloid leukemia (AML) when treated with chemotherapy alone. However, th
Autor:
Jishi Wang, Michael Schmitt, William Krüger, Maria-Luisa Schubert, Sanmei Wang, Volker Eckstein, Peter Dreger, Carsten Müller-Tidow, Lei Wang, Thomas Luft, Stefan Schönland, Brigitte Neuber, Angela Hückelhoven-Krauss, Tim Sauer, Ming Ni, Ute Hegenbart, Wenjie Gong, Yuntian Ding, Anita Schmitt
Publikováno v:
Cytotherapy. 24:311-319
Extracorporeal photopheresis (ECP), a personalized cellular immunotherapy, constitutes a promising treatment for steroid-refractory/-resistant graft-versus-host disease (SR-GvHD), with encouraging clinical response rates. To further investigate its m
Autor:
Lequina Myles, Terry David Church
Publikováno v:
Cytotherapy. 24:344-355
Background aims The novelty of cell and gene therapies (CGTs) has introduced unique supply chain challenges and considerations not seen by chemically synthesized (small-molecule) drugs. These complexities increase during the clinical phases, where dr
Publikováno v:
Cytotherapy. 24:225-234
Background aims Several studies have shown the efficacy of mesenchymal stem cell (MSC) therapy for lower extremity vascular disease (LEVD) in diabetic patients, but the results are not consistent. Therefore, the authors conducted a meta-analysis of r
Autor:
Atsuko Shono, Coenraad K van Kalken, Peter J. van der Spek, Eric P Krenning, Toru Kotani, Djo Hasan
Publikováno v:
Purinergic Signalling
Purinergic Signalling, 18(1), 13-59. Springer Netherlands
Purinergic Signalling, 18(1), 13-59. Springer Netherlands
Hyperinflammation plays an important role in severe and critical COVID-19. Using inconsistent criteria, many researchers define hyperinflammation as a form of very severe inflammation with cytokine storm. Therefore, COVID-19 patients are treated with
Autor:
Nicole Mittman, Craig C. Earle, Brian Leber, Dina Khalaf, Mohammed Siddiqui, Matthew C. Cheung, Mitchell Sabloff, Lisa Chodirker, Grace Christou, Qing Li, Eugene Brailovski, Alexandre Mamedov, Anne Parmentier, Ning Liu, Lee Mozessohn, Karen W.L. Yee, Ying Liu, Liying Zhang, Rena Buckstein
Publikováno v:
Annals of Hematology. 101:1023-1030
Background: Observational studies suggest an anti-neoplastic effect associated with statins, metformin, dipeptidyl peptidase-4 inhibitors (DPP4i), while sulfonylureas may have a neutral or detrimental effect. The aim of this study was to determine th
Publikováno v:
Current Oncology. 29:892-900
Background: The use of virtual care, defined as providing healthcare in ways other than in-person visits, dramatically increased during the COVID-19 pandemic to minimize infection risk and maintain care provision. However, the majority of studies eva
Autor:
Kimberly R. Jordan, Stephanie Rawlings-Rhea, Ashley Wilson, Annie Luong, Hema Dave, Hisham Abdel-Azim
Publikováno v:
Cytotherapy
Immune effector cell (IEC) therapies have revolutionized our approach to relapsed B-cell malignancies, and interest in the investigational use of IECs is rapidly expanding into other diseases. Current challenges in the analysis of IEC therapies inclu
Autor:
Xiao-Li Zheng, Hengxiang Wang, Ning Mao, Dong-Mei Han, Heng Zhu, Hong-Min Yan, Zi-Kuan Guo, Mei Xue, Ling Zhu, Jing Liu, Hong-Mei Ning, Li Ding
Publikováno v:
Cytotherapy. 24:205-212
Background aims Despite the great advances in immunosuppressive therapy for severe aplastic anemia (SAA), most patients are not completely cured. Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) has been recommended as an alternati