Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sergio Valente"'
Autor:
Denyse Bagrel, Marc Diederich, Gilbert Kirsch, Patrick Chaimbault, Sergio Valente, Claudia Cerella, Emilie Bana, Mario Dicato, Estelle Sibille
Publikováno v:
Molecular Carcinogenesis. 54:229-241
Cell division cycle (CDC) 25 proteins are key phosphatases regulating cell cycle transition and proliferation by regulating CDK/cyclin complexes. Overexpression of these enzymes is frequently observed in cancer and is related to aggressiveness, high-
Autor:
Francesco Spallotta, Carlo Gaetano, Antonello Mai, Andreas M. Zeiher, Fabio Martelli, Sergio Valente, Chiara Cencioni
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 17643-17663 (2013)
International Journal of Molecular Sciences; Vol 14
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 17643-17663 (2013)
International Journal of Molecular Sciences; Vol 14
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, elderly people are increasing. This trend is particularly evident in Western countries, where healthier living conditions and better cures are availab
Autor:
Fabio Manzo, Sergio Valente, Angela Nebbioso, Antonello Mai, Lucia Altucci, Annamaria Scognamiglio
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2008, 1783 (10), pp.2030-8. ⟨10.1016/j.bbamcr.2008.07.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2008, 1783 (10), pp.2030-8. ⟨10.1016/j.bbamcr.2008.07.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2008, 1783 (10), pp.2030-8. ⟨10.1016/j.bbamcr.2008.07.007⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2008, 1783 (10), pp.2030-8. ⟨10.1016/j.bbamcr.2008.07.007⟩
International audience; Discovered for their ability to deacetylate histones and repress transcription, HDACs are a promising target for therapy of human diseases. The class II HDACs are mainly involved in developmental and differentiation processes,