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Autor:
Darya O. Kuzmina, Ekaterina V. Nekrasova, Vladimir S. Shavva, Igor V. Kudriavtsev, Ekaterina E. Larionova, Katerina V. Danko, S. V. Orlov
Publikováno v:
Biochemistry (Moscow). 86:1201-1213
Apolipoprotein A-I (ApoA-I) is a key component of reverse cholesterol transport in humans. In the previous studies, we demonstrated expression of the apoA-I gene in human monocytes and macrophages; however, little is known on the regulation of the ap
Publikováno v:
Biochemistry (Moscow). 85:1310-1318
The global problem of emerging resistance of microorganisms to antibiotics makes the search for new natural substances with antibacterial properties relevant. Such substances include peptidoglycan recognition proteins (PGLYRP), which are the componen
Autor:
K T Turpaev
Publikováno v:
Biochemistry (Moscow). 85:54-67
KLF2 is a member of the Krüppel-like transcription factor family of proteins containing highly conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and regulation of the functional activity of monocytes, T lymphocytes,
Autor:
K T Turpaev
Publikováno v:
Biochemistry (Moscow). 83:863-873
Translation factor eIF5A participates in protein synthesis at the stage of polypeptide chain elongation. Two eIF5A isoforms are known that are encoded by related genes whose expression varies significantly in different tissues. The eIF5A1 isoform is
Publikováno v:
Biochemistry (Moscow). 82:606-612
Sex-determining region Y-box 9 (Sox9) is an important transcription factor that has been identified as a key regulator of several types of diseases. In this study, we explored the correlation of Sox9 with cell proliferation, apoptosis, inflammatory f
Publikováno v:
Biochemistry (Moscow). 81:1676-1697
This review discusses and summarizes the results of molecular and cellular investigations of myosin light chain kinase (MLCK, MYLK1), the key regulator of cell motility. The structure and regulation of a complex mylk1 gene and the domain organization
Autor:
A. Yu. Ratushnyy, Ludmila Buravkova
Publikováno v:
Doklady Biochemistry and Biophysics. 477:354-356
The expression of 84 focal adhesion genes of multipotent mesenchymal stromal cells (MMSCs) after 96-h microgravity simulation at 3D clinorotation was studied. The upregulation of ITGA6, ITGA7, BCAR1, GRB2, CAV1, and DIAPH1 and the downregulation of I
Autor:
William G. Telford, Alexander M. Sapozhnikov, Leonid M. Kanevskiy, Maria A. Streltsova, Elena I. Kovalenko, S. A. Erokhina
Publikováno v:
Biochemistry (Mosc)
NK cells play an important regulatory role in sepsis by induction and augmentation of proinflammatory reactions in early stages of the septic process and by suppression of immune response in later stages of inflammation. The present work was aimed at
Publikováno v:
Biochemistry (Moscow). 76:1402-1433
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the participation of YB-1 in DNA reparation and transcription, mRNA splic
Exogenous 26S proteasomes can enter living cells to influence gene expression in the recipient cells
Autor:
Yu. Ya. Vatazhok, A. S. Tsimokha, Mittenberg Ag, Evteeva In, L. N. Gause, Yu. B. Ermolaeva, Valentina A. Kulichkova, I. V. Kozhukharova, Konstantinova Im
Publikováno v:
Doklady Biological Sciences. 423:464-468