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Publikováno v:
Journal of Cellular and Molecular Medicine
Diabetic nephropathy (DN) is still on the rise worldwide, and millions of patients have to be treated through dialysis or transplant because of kidney failure caused by DN. Recent reports have highlighted circRNAs in the treatment of DN. Herein, we a
Autor:
Yu-Hsun Kao, Shih-Yu Huang, Yao Chang Chen, Yi-Jen Chen, Shih Ann Chen, Yung-Kuo Lin, Yen-Yu Lu, Satoshi Higa
Publikováno v:
Journal of Cellular and Molecular Medicine
Chronic kidney disease (CKD) increases the risk of arrhythmia. The right ventricular outflow tract (RVOT) is a crucial site of ventricular tachycardia (VT) origination. We hypothesize that CKD increases RVOT arrhythmogenesis through its effects on ca
Autor:
Shijian Xiang, Ronghua Yang, Ning Gu, Xiaobing Pi, Bo Liang, Jiehua Li, Kai Yu, Sitong Zhou, Xiaodong Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
Skin cutaneous melanoma (SKCM) is one of the most destructive skin malignancies and has attracted worldwide attention. However, there is a lack of prognostic biomarkers, especially tumour microenvironment (TME)‐based prognostic biomarkers. Therefor
Publikováno v:
Journal of Cellular and Molecular Medicine
Accumulating evidence during the last two decades has addressed the potential anti‐inflammatory properties of berberine (BBR), a bioactive alkaloid compound isolated from Coptidis rhizoma, in controlling or treating several inflammatory diseases. P
Autor:
Maryam Salimi, Mohammad Mahdi Majidi, Elham Roshandel, Sarvenaz Samadi Kochaksaraei, Abbas Hajifathali, Farshid Alaeddini, Sepide Kazemi, Nasser Aghdami, Behnam Sadeghi, Olle Ringdén, Ali Pirsalehi, Hoda Sadrosadat, Ghazaleh Sankanian
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute respiratory distress syndrome (ARDS) is the most common cause of death in COVID‐19 patients. The cytokine storm is the main driver of the severity and magnitude of ARDS. Placenta‐derived decidua stromal cells (DSCs) have a stronger immunosu
Autor:
Chi Liu, Leyuan Wang, Xiangping Qu, Ming Yang, Xizi Du, Lin Yuan, Gelei Xiao, Yang Xiang, Ling Qin, Kai Zhou, Huijun Liu, Wenkai Li, Xiaoqun Qin, Yu Yang
Publikováno v:
Journal of Cellular and Molecular Medicine
Respiratory syncytial virus (RSV) infection in airway epithelial cells is the main cause of bronchiolitis in children. Excessive mucus secretion is one of the primary symbols in RSV related lower respiratory tract infections (RSV‐related LRTI). How
Autor:
Xiaolong Ma, Kemin Liu, Yang Liu, Cheng Zhao, Yan Yao, Yichen Zhao, Meng Xin, Quan Liu, Yue Ma, Shuyun Bai, Pengfei Chen, Jiangang Wang, Qing Ye, Chen Bai, Caiwu Zeng
Publikováno v:
Journal of Cellular and Molecular Medicine
Alteration of tissue inhibitors of matrix metalloproteinases (TIMP)/matrix metalloproteinases (MMP) associated with collagen upregulation has an important role in sustained atrial fibrillation (AF). The expression of miR‐146b‐5p, whose the target
Autor:
Mitra Ayyasi, Golnaz Goodarzi, Sadra Samavarchi Tehrani, Mohsen Ebrahimi, Arghavan Zebardast, mohammad taha saadati rad
Publikováno v:
Cell Biochemistry and Function
New coronavirus disease 2019 (COVID-19), as a pandemic disaster, has drawn the attention of researchers in various fields to discover suitable therapeutic approaches for the management of COVID-19 patients. Currently, there are many worries about the
Autor:
Di Wu, Rutong Yu, Ji Qi, Qingming Meng, Yu Zhang, Kai Wang, Qiang Wang, Xu Wang, Xiang Wang, Xiuping Zhou, Er Nie, Yan Wang, Ding Zhou
Publikováno v:
Journal of Cellular and Molecular Medicine
Patients with malignant glioma often suffered from depression, which leads to an increased risk of detrimental outcomes. Imipramine, an FDA‐approved tricyclic antidepressant, has been commonly used to relieve depressive symptoms in the clinic. Rece
Publikováno v:
Journal of Cellular and Molecular Medicine
Mesenchymal stem/stromal cells isolated from human term placenta (pMSCs) have potential to treat clinically manifested inflammatory diseases. Atherosclerosis is a chronic inflammatory disease, and platelets play a contributory role towards its pathog