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Publikováno v:
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 13, Iss 1, p 100 (2012)
BMC Musculoskeletal Disorders, Vol 13, Iss 1, p 100 (2012)
Background Hmg-CoA reductase inhibitors (statins) are widely used to prevent disease associated with vascular disease and hyperlipidemia. Although side effects are uncommon, clinical observations suggest statin exposure may exacerbate neuromuscular d
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 8, Iss 1, p 119 (2011)
Journal of Neuroinflammation, Vol 8, Iss 1, p 119 (2011)
Background Recent data indicate that inflammatory mechanisms contribute to diabetic retinopathy (DR). We have determined that serine racemase (SR) expression is increased by inflammatory stimuli including liposaccharide (LPS), amyloid β-peptide (A-b
Autor:
Rick Shin, Satoshi Ikemoto
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 11, Iss 1, p 101 (2010)
BMC Neuroscience, Vol 11, Iss 1, p 101 (2010)
Background Picrotoxin blocks GABAA receptors, whose activation typically inhibits neuronal firing activity. We recently found that rats learn to selectively self-administer picrotoxin or bicuculline, another GABAA receptor antagonist, into the supram
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 6, Iss 1, p 37 (2009)
Journal of Neuroinflammation, Vol 6, Iss 1, p 37 (2009)
Background Glucocorticoids have been shown to be effective in the treatment of autoimmune diseases of the CNS such as multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). However, the mechanisms and the site of gl
Autor:
Kirsty Bannister, Wahida Rahman, Anthony H. Dickenson, Annette C. Dolphin, Jean-Laurent Vonsy, Claudia S. Bauer
Publikováno v:
Molecular Pain
Molecular Pain, Vol 5, Iss 1, p 45 (2009)
ResearcherID
Molecular Pain, Vol 5, Iss 1, p 45 (2009)
ResearcherID
Background Descending facilitation, from the brainstem, promotes spinal neuronal hyperexcitability and behavioural hypersensitivity in many chronic pain states. We have previously demonstrated enhanced descending facilitation onto dorsal horn neurone
Autor:
Frédéric Becq, Patricia Melin, Caroline Norez, Clarisse Vandebrouck, Yvette Mettey, Renaud Robert, Christelle Guibert
Publikováno v:
Respiratory Research
Respiratory Research, BioMed Central, 2006, 7, pp.113. ⟨10.1186/1465-9921-7-113⟩
Respiratory Research, 2006, 7, pp.113. ⟨10.1186/1465-9921-7-113⟩
Respiratory Research, Vol 7, Iss 1, p 113 (2006)
Respiratory Research, BioMed Central, 2006, 7, pp.113. ⟨10.1186/1465-9921-7-113⟩
Respiratory Research, 2006, 7, pp.113. ⟨10.1186/1465-9921-7-113⟩
Respiratory Research, Vol 7, Iss 1, p 113 (2006)
Background The airway functions are profoundly affected in many diseases including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). CF the most common lethal autosomal recessive genetic disease is caused by mutations of
Autor:
Sergio R. Ojeda, Lars Kunz, Ignaz Wessler, Annette Krieger, Abraham Amsterdam, Becky J. Proskocil, Gregory A. Dissen, Artur Mayerhofer, Eliot R. Spindel
Publikováno v:
Reproductive Biology and Endocrinology
Reproductive Biology and Endocrinology, Vol 4, Iss 1, p 37 (2006)
Reproductive Biology and Endocrinology, Vol 4, Iss 1, p 37 (2006)
Background It has been previously shown that cultured granulosa cells (GCs) derived from human ovarian preovulatory follicles contain choline acetyltransferase (ChAT), the enzyme responsible for acetylcholine (ACh) synthesis. They also produce ACh an