Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hua Zhang"'
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 49(2)
This study aimed to investigate the synergistic effect of lidamycin (LDM) and rituximab on human B cell lymphoma Ramos cells. Cell proliferation was measured using MTS assay, cell apoptosis was analyzed by Annexin V-FITC/PI assay, the expression of a
[Anticancer effect of 17-(6-cinnamamido-hexylamino-)-17-demethoxygeldanamycin: in vitro and in vivo]
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 48(12)
In the present study, a new compound named 17-(6-cinnamamido-hexylamino-)-17-demethoxygeldanamycin (CDG) was obtained by introducing the cinnamic acid (CA) group into the 17-site of geldanamycin (GDM). The anti-cancer effects of CDG in vitro and in v
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 46(1)
This study is to investigate the inhibitory effect of lidamycin (LDM) and its combination with methotrexate (MTX) on lung metastasis of fibrosarcoma by bioluminescence imaging in athymic mice. A stable luciferase transfected HT-1080 cell line was con
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 44(3)
In this study, the antitumor activities of VEGF shRNA and tubulin inhibitors on human prostate cancer DU145 cells was investigated, and shRNA transient expression plasmid pCSH1-VEGF targeting VEGF mRNA was constructed. The silence efficiency of pCSH1
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 43(6)
To investigate the effect of lidamycin (LDM) on human gastric carcinoma BGC823 cells and xenograft growth in nude mice, MTT (methyl thiazolyl tetrazolium) assay was used to determine the inhibition of BGC823 cell proliferation by LDM. Induction of ap
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 39(10)
To search for new compounds with strong anti-inflammatory activity and low gastrointestinal (GI) side effects.A series of p-(methanesulfonyl) styrene-linked cyclic ketone derivatives were synthesized. Their anti-inflammatory activities against xylene
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 39(7)
To investigate the inhibitory activity of salvianolic acid A (SAA) on nucleoside transport in cancer cells and its antitumor effect.[3H] thymidine and [3H] uridine transport assays were used to determine the inhibitory activity on nucleoside transpor
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 38(9)
To search for new compounds with strong anti-inflammatory activity and low gastrointestinal (GI) side effects.A series of alpha-substituted p-(methanesulfonyl) phenyl-propenamides were synthesized. Their anti-inflammatory activities against xylene-in
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 37(1)
To search for new derivatives of diclofenac (DC) having higher potency than the parent drug and lacking its undesirable effects.Coupling DC with NO donor 3-hydroxymethyl-4-phenylfuroxan and its isomer through esterification, evaluating anti-inflammat