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Autor:
Yang Song, Robert K. Ernst, Stefanie N. Vogel, W.Y.C. Lai, Darren J. Perkins, Shreeram C. Nallar, Lynn D. Hawkins, Kari Ann Shirey, Erin Harberts, Anup Mahurkar, Katharina Richard, Archana Gopalakrishnan, Alexandra Vlk
Publikováno v:
Vaccine
Toll-like receptors (TLRs), a family of "pattern recognition receptors," bind microbial and host-derived molecules, leading to intracellular signaling and proinflammatory gene expression. TLR4 is unique in that ligand-mediated activation requires the