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pro vyhledávání: ''
Autor:
Hirotsugu Isaka, Manami Tada, Masakazu Toi, Hironobu Sasano, Takayuki Ueno, Kaisuke Miyamoto, Tomohiro Chiba, Shigeru Imoto, Hiroshi Kamma, Kentaro Imi, Shigehira Saji, Hiroki Itoh
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 40(10)
Breast cancer has been suggested to have two distinct driving mechanisms: the hormone receptor and the growth factor receptor pathways. We hypothesized that each driving system produces a different expression pattern of estrogen-regulated genes, such
Autor:
Zhi-cheng Yang, Yongyuan Liu, Wennan Huang, Baoying Chen, Ying Zhang, Yuzhou Wang, Yijin Zhou
Publikováno v:
Tumor Biology, Vol 39 (2017)
Long non-coding RNAs recently were identified as key mediators of cancer metastasis. This study provided evidence that long non-coding RNA MALAT1 was up-regulated in breast cancer tissues and cell lines. MALAT1 promoted cancer cell invasion through i
Autor:
Jiang Du, Jian Wang, Guang-Ping Wu, Xiaoying Zheng, Huanyu Zhao, Yang Han, Enhua Wang, Lian-He Yang
Publikováno v:
Tumor Biology, Vol 39 (2017)
IQ-domain GTPase-activating protein 1 is a scaffolding protein with multidomain which plays a role in modulating dishevelled (Dvl) nuclear translocation in canonical Wnt pathway. However, the biological function and mechanism of IQ-domain GTPase-acti
Effect of NIMA-related kinase 2B on the sensitivity of breast cancer to paclitaxel in vitro and vivo
Publikováno v:
Tumor Biology, Vol 39 (2017)
NIMA-related kinase 2B has been known to be an important centrosome regulatory factor. The aim of this study was to investigate the effect of NIMA-related kinase 2B on the sensitivity of breast cancer to paclitaxel. We detected the expression of NIMA
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(10)
Metastasis has become the main challenge for treatment of estrogen receptor alpha (ERα) negative breast cancer. Here, we found a negative correlation between miR-497 and estrogen-related receptor alpha (ERRα), a nuclear receptor overexpressed in ER
Autor:
Rubens Cecchini, Carolina Panis, Aedra Carla Bufalo, Luciana Pizzatti, Eliana Abdelhay, A. C. S. A. Herrera, Vanessa Jacob Victorino
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(3)
Chemotherapy remains the first-choice option for adjuvant therapy in breast cancer. Here, we investigated the impact of the first chemotherapic cycle of doxorubicin on the plasmatic-proteomic profiling of women diagnosed with breast cancer (n = 87).
Autor:
Qingfu Zhang, Yang Guo, Xiaohong Liu, Feng Jin, Xiaoyun Mao, Yanan Sun, Peng Su, Liang Feng, Hao Chen
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(4)
TSTA3 participates in enzyme metabolism and affects glycosylation processes, and abnormal glycosylation influences the malignant transformation of cells and tumor development. However, studies have not examined the molecular biological function of TS
Autor:
Wermerson Assunção Barroso, Vanessa Jacob Victorino, Carolina Panis, S. Ariga, Heraldo Possolo de Souza, Bruno Chausse, Ricardo Costa Petroni, A K M Assunção, Isabela Casagrande Jeremias, A. C. S. A. Herrera, Thais Martins de Lima, Vivian Cury
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(5)
Breast cancer is a prevalent neoplastic disease among women worldwide which treatments still present several side effects and resistance. Considering that cancer cells present derangements in their energetic homeostasis, and that peroxisome prolifera
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 36(10)
Breast cancer survival was associated with higher frequencies of CD8(+) T cytotoxic T cells in infiltrating lymphocytes. On the other hand, the frequency of CD4(+)CD25(+)FoxP3(+) regulatory T cells was inversely correlated with clinical outcomes of b
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 36(5)
Overexpression of Hox transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA (lncRNA), is associated with cancer cell proliferation, invasion, progression, and metastasis as well as poor survival in a variety of human cancers including b