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Publikováno v:
Tumour Biology
The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D. A great number of studies regarding the association between BsmI polymorphism in the VDR gene and breast cancer have been published. However, the results have b
Autor:
Michał Matysiewicz, Anna Cieślińska, Jadwiga Snarska, Michał Tenderenda, Konrad Wroński, Elżbieta Kostyra, Edyta Sienkiewicz-Szłapka, Ewa Fiedorowicz, Beata Jarmołowska
Publikováno v:
Tumour Biology
Structure-dependent μ-opioid receptor (MOR) activity is an important element in cancer opioid analgesic effectiveness. It is widely accepted that guanine (G) substitution for adenine (A) at OPRM1 gene sequence position 118 changes receptor glycosyla
Autor:
Marcia Batista Salzgeber, T. T Benvenuti, João Carlos Sampaio Góes, Maria Lucia Hirata Katayama, Maria Aparecida Azevedo Koike Folgueira, Paulo Roberto Del Valle, Jane Haruko Lima Kaiano, Rosângela Portilho Costa Santos, Suzana Terumi Honda, Dirce Maria Carraro, Patricia Bortman Rozenchan, E. C. Lyra, Maria Mitzi Brentani, Cesar Torres, Helena Brentani
Publikováno v:
Tumour Biology
Our aim was to evaluate the interaction between breast cancer cells and nodal fibroblasts, by means of their gene expression profile. Fibroblast primary cultures were established from negative and positive lymph nodes from breast cancer patients and
Autor:
Feng Jin, Fan Yao, Yanan Sun, Ayao Guo, Chong Liu, Quanxiu Jin, Chuifeng Fan, Xiaoyun Mao, Bo Li, Shu Guan
Publikováno v:
Tumour Biology
CXCR4 and its ligand CXCL12 can promote the proliferation, survival, and invasion of cancer cells. They have been shown to play an important role in regulating metastasis of breast cancer to specific organs. High CXCR4 expression was also correlated
Publikováno v:
Tumour Biology
The association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and breast cancer risk in the Chinese population has been widely reported, but results were inconsistent. In order to derive a more precise estimation of the relat
Autor:
Andrzej K. Bednarek, Maciej J. Żelazowski, Grażyna Pasz-Walczak, Radzisław Kordek, Elżbieta Płuciennik, Piotr Potemski
Publikováno v:
Tumour Biology
The WWOX gene is a tumour suppressor gene affected in various types of malignancies. Numerous studies showed either loss or reduction of the WWOX expression in variety of tumours, including breast, ovary, liver, stomach and pancreas. Recent study dem