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Autor:
Robert Beck, Javier Cortes, Nadia Harbeck, J.-M. Nabholtz, Amy Ko, Markus F. Renschler, Stefan Glück, Robert E. Coleman, Denise A. Yardley, Debora Barton, Joyce O'Shaughnessy, Adam Brufsky, Pierfranco Conte
Publikováno v:
Trials
Background Triple-negative breast cancer is an aggressive disease with unmet clinical needs. In a phase III study of patients with metastatic triple-negative breast cancer, first-line gemcitabine/carboplatin resulted in a median progression-free surv
Autor:
Patrizia Gnagnarella, Fabio Bassi, Daniele Dragà, Maria Claudia Simoncini, Ketti Mazzocco, F. Baggi, Annarita Sabbatini, Gabriella Pravettoni, Patrick Maisonneuve
Publikováno v:
Trials
Most women with breast cancer experience a progressive weight gain during and after treatment. Obesity is associated with an increased risk of recurrence, contralateral breast cancer, and death. Physical activity after cancer diagnosis has been repor
Publikováno v:
Trials
In an international trial of premenopausal women with hormone receptor positive operable breast cancer that compares how the timing of surgical oophorectomy and mastectomy affects time to recurrence, we re-evaluated the required sample size near the
Autor:
Kate Butler, Toni Zhong, Shaghayegh Bagher, Stefan O.P. Hofer, Coimbatore Srinivas, Anne C. O'Neill, Hance Clarke, Marie Ojha, Stuart A. McCluskey
Publikováno v:
Trials
Background Breast reconstruction using the free muscle-sparing transversus abdominus myocutaneous or deep inferior epigastric perforator flaps are common methods for restoring mastectomy defects for breast cancer patients. Despite its increasing popu
Autor:
Annmarie Nelson, Peter Barrett-Lee, Gareth Griffiths, Deborah Fenlon, Catherine Sampson, Nick Murray, Emily Harrop, Duncan Wheatley, Jenny Morris, Kerenza Hood
Publikováno v:
Trials
Background This qualitative sub-study aimed to explore the experiences of participants on the National Cancer Research Institute ZICE clinical trial, a randomised trial assessing two types of bisphosphonate treatment in breast cancer patients with bo