Zobrazeno 1 - 10
of 14
pro vyhledávání: '"John S"'
Publikováno v:
Transplantation. 50:487-492
This study was designed to investigate aspects of renal xenobiotic metabolism and the renal cellular response to drug-induced injury, in mediating cyclosporine nephrotoxicity. The relation between CsA and renal enzyme activity has not previously been
Autor:
John S. Najarian, William D. Payne, P. S. Almond, David E.R. Sutherland, Christoph Troppmann, Kristen J. Gillingham, Arthur J. Matas, David L. Dunn
Publikováno v:
Transplantation. 52(2)
Second renal allograft survival rates are lower than those of primary allografts. For recipients immunosuppressed with azathioprine, prednisone, and Minnesota ALG (conventional immunosuppression), risk factors associated with decreased second graft s
Autor:
Arthur J. Matas, Nancy L. Reinsmoen, John S. Najarian, David E.R. Sutherland, Fritz H. Bach, Dixon B. Kaufman
Publikováno v:
Transplantation. 50(5)
Previous studies indicate some kidney allograft recipients treated with total lymphoid irradiation, cyclosporine, or conventional immunosuppressive therapy demonstrate specific proliferative unresponsiveness in mixed lymphocyte culture (MLC) to donor
Publikováno v:
Transplantation. 43:73-78
Pancreas allograft rejection in dogs with pancreaticocystostomy can be predicted in advance of hyperglycemia by monitoring the urinary amylase (UA) concentration (U/L): In initial experiments, UA values declined to less than 1000 1.3 +/- 0.2 days bef
Autor:
Jean-Paul Squifflet, John S. Najarian, John Heil, J. Field, David E.R. Sutherland, John J. Rynasiewicz
Publikováno v:
Transplantation. 34:315-318
Cyclosporin A (Cy A) by itself is limited in its clinical application by its dose-related liver and kidney toxicity. Combining Cy A with prednisone allows lower doses of Cy A to be used, but the side effects of steroids are cumulative. Thus, we teste
Autor:
Barbara Flick, William D. Payne, John S. Najarian, David S. Fryd, Richard L. Simmons, Daniel M. Canafax, David E.R. Sutherland, Nancy L. Ascher, Christopher P. Johnson
Publikováno v:
Transplantation. 45:380-385
Between September 1980 and June 1984, 246 splenectomized, transfused renal allograft recipients were stratified according to presence of diabetes and donor source, and randomized to treatment with either cyclosporine (CsA)-prednisone (pred) or antily
Autor:
Daniel M. Canafax, William D. Payne, David E.R. Sutherland, John Heil, Richard L. Simmons, Nancy L. Ascher, Armando Torres, Davis S. Fryd, John S. Najarian, Marilyn H. Strand
Publikováno v:
Transplantation. 41:177-181
We randomized 158 recipients of cadaver renal allografts to cyclosporine-prednisone (83) or antilymphocyte globulin-azathioprine-prednisone (75) to evaluate: the effects of immunosuppression and pretransplant risk factors on the incidence of delayed
Autor:
David E.R. Sutherland, David S. Fryd, John S. Najarian, Richard L. Simmons, Charles E. Morrow, Ronald M. Ferguson
Publikováno v:
Transplantation. 34:319-325
From January 1968 to December 1981, 470 uremic diabetic patients received primary renal allografts at the University of Minnesota. Until 1979, the patient and graft survival rates were less good in diabetic than in nondiabetic recipients. Since 1979,
Publikováno v:
Transplantation. 34:330-338
Forty-nine pancreas transplants were performed in 45 patients between July 23, 1978 and May 14, 1982, 18 from related donors. Currently (June 1982), 13 patients have functioning grafts and are insulin independent between 1 and 46 months after transpl
Autor:
David E.R. Sutherland, Mark D. Pescovitz, Richard L. Simmons, William D. Payne, John S. Najarian, Scott A. Gruber, Nancy L. Ascher, David S. Fryd
Publikováno v:
Transplantation. 44:775-777
The incidence of arterial and venous thromboembolic complications was compared in 224 renal allograft recipients who were prospectively randomized and stratified by risk to treatment with either cyclosporine-prednisone (CsA-P) (n = 117) or azathiopri