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Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Increasing evidences supported that subjective cognitive decline (SCD) might be a potential first symptomatic manifestation of Alzheimer’s disease (AD). The rapidly growing number of SCD individuals who seek medical help and advice also makes it ur
Autor:
Chen, Shi Dong, Lu, Jia Ying, Li, Hong Qi, Yang, Yu Xiang, Jiang, Jie Hui, Cui, Mei, Zuo, Chuan Tao, Tan, Lan, Dong, Qiang, Yu, Jin Tai, Weiner, Michael W., Aisen, Paul, Petersen, Ronald, Jack, Clifford R., Jagust, William, Trojanowki, John Q., Toga, Arthur W., Beckett, Laurel, Green, Robert C., Saykin, Andrew J., Morris, John C., Perrin, Richard J., Shaw, Leslie M., Carrillo, Maria, Potter, William, Barnes, Lisa, Bernard, Marie, González, Hector, Ho, Carole, Hsiao, John K., Jackson, Jonathan, Masliah, Eliezer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Medical Biophysics Publications
Translational Psychiatry
Medical Biophysics Publications
A biological research framework to define Alzheimer’ disease with dichotomized biomarker measurement was proposed by National Institute on Aging–Alzheimer’s Association (NIA–AA). However, it cannot characterize the hierarchy spreading pattern
Autor:
David C. Page, Alan J. Gow, Ian J. Deary, Olivia K.L. Hamilton, M. del C. Valdés-Hernández, Paul Redmond, Simon R. Cox, Joanna M. Wardlaw, Adele M. Taylor, Lucia Ballerini, Janie Corley, Mark E. Bastin, S. Muñoz Maniega, F. Conte, Judith A. Okely
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Hamilton, O, Cox, S R, Okely, J, Conte, F, Ballerini, L, Bastin, M E, Corley, J, Taylor, A, Page, D, Gow, A, Muñoz Maniega, S, Redmond, P, Valdés Hernández, M C, Wardlaw, J M & Deary, I J 2021, ' Cerebral Small Vessel Disease Burden and Longitudinal Cognitive Decline from age 73 to 82: the Lothian Birth Cohort 1936 ', Translational Psychiatry . https://doi.org/10.1038/s41398-021-01495-4
Transl Psychiatry.
Translational Psychiatry
Hamilton, O, Cox, S R, Okely, J, Conte, F, Ballerini, L, Bastin, M E, Corley, J, Taylor, A, Page, D, Gow, A, Muñoz Maniega, S, Redmond, P, Valdés Hernández, M C, Wardlaw, J M & Deary, I J 2021, ' Cerebral Small Vessel Disease Burden and Longitudinal Cognitive Decline from age 73 to 82: the Lothian Birth Cohort 1936 ', Translational Psychiatry . https://doi.org/10.1038/s41398-021-01495-4
Transl Psychiatry.
Translational Psychiatry
Slowed processing speed is considered a hallmark feature of cognitive decline in cerebral small vessel disease (SVD); however, it is unclear whether SVD’s association with slowed processing might be due to its association with overall declining gen
Autor:
Forugh Salimi Dafsari, Frank Jessen
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry 10(1), 160 (2020). doi:10.1038/s41398-020-0839-1
Translational Psychiatry
Translational Psychiatry 10(1), 160 (2020). doi:10.1038/s41398-020-0839-1
Translational Psychiatry
It is broadly acknowledged that the onset of dementia in Alzheimer’s disease (AD) may be modifiable by the management of risk factors. While several recent guidelines and multidomain intervention trials on prevention of cognitive decline address li
Autor:
Debra A. Fleischman, Lei Yu, Robert S. Wilson, David A. Bennett, Philip L. De Jager, Hongyu Zhao, Xiaoqing Yu, Turhan Canli
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-9 (2018)
Translational Psychiatry
Translational Psychiatry
Subjective social isolation, loneliness, is associated with poor mental and physical health, but the underlying molecular mechanisms are poorly understood. Here we analyzed loneliness data collected on average 5 years ante-mortem and RNA gene express