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Autor:
Markus J. Hofer, Samantha J. Lain, Velda X. Han, Natasha Nassar, Shekeeb S. Mohammad, Hannah F Jones, Russell C. Dale, Wendy A. Gold, Shrujna Patel, Timothy C Nielsen, Fabienne Brilot
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
Inflammation is increasingly recognized as a cause or consequence of common problems of humanity including obesity, stress, depression, pollution and disease states such as autoimmunity, asthma, and infection. Maternal immune activation (MIA), trigge
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Translational Psychiatry
Translational Psychiatry
Patients with late-onset Alzheimer’s disease (LOAD) frequently manifest comorbid neuropsychiatric symptoms with depression and anxiety being most frequent, and individuals with major depressive disorder (MDD) have an increased prevalence of LOAD. T
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-12 (2020)
Translational Psychiatry
Translational Psychiatry
Epigenetic variation in peripheral tissues is being widely studied as a molecular biomarker of complex disease and disease-related exposures. To date, few studies have examined differences in DNA methylation associated with attention-deficit hyperact
Autor:
Debra A. Fleischman, Lei Yu, Robert S. Wilson, David A. Bennett, Philip L. De Jager, Hongyu Zhao, Xiaoqing Yu, Turhan Canli
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-9 (2018)
Translational Psychiatry
Translational Psychiatry
Subjective social isolation, loneliness, is associated with poor mental and physical health, but the underlying molecular mechanisms are poorly understood. Here we analyzed loneliness data collected on average 5 years ante-mortem and RNA gene express
Autor:
Klaus Oliver Schubert, Azmeraw T. Amare, Manuela Klingler-Hoffmann, Bernhard T. Baune, Sarah Cohen-Woods
Publikováno v:
Translational Psychiatry
Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene studies have identified genetic variants associated with cardiovascular diseases, metabolic diseases and mood disorders. Although previous efforts were successful for in
Autor:
Klaus Berger, Volker Arolt, Walter Heindel, Heike Wersching, Bernhard T. Baune, Ashley Gilmour, Michael J Stuart
Publikováno v:
Translational Psychiatry
A compelling association has been observed between cardiovascular disease (CVD) and depression, suggesting individuals with depression to be at significantly higher risk for CVD and CVD-related mortality. Systemic immune activation, hypothalamic–pi