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Autor:
Ivana Rosenzweig, Goran Sedmak, Katarina Ilić, Kristina Mlinac-Jerković, Svjetlana Kalanj-Bognar
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Translational Psychiatry
Translational Psychiatry
Synaptic glycoprotein neuroplastin is involved in synaptic plasticity and complex molecular events underlying learning and memory. Studies in mice and rats suggest that neuroplastin is essential for cognition, as it is needed for long-term potentiati
Autor:
Nina S. Levy, Itamar Kahn, Andrew P. Levy, Eyal Bergmann, Alexandra Kavushansky, Daniela Lichtman, Nadav Cohen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Translational Psychiatry
Translational Psychiatry
IQSEC2 is an X-linked gene which is associated with autism spectrum disorder (ASD), intellectual disability and epilepsy. IQSEC2 is a postsynaptic density protein, localized on excitatory synapses as part of the NMDA receptor complex and is suggested
Autor:
Yen-Wei Chen, Clarissa M. Liu, Scott E. Kanoski, Christine A. Olson, Roshonda B. Jones, Xia Yang, Elaine Y. Hsiao, Emily E. Noble, Ruth Schade, Elizabeth A. Davis, Claire B. de La Serre, Andrea N. Suarez, Linda Tsan
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-16 (2021)
Translational Psychiatry
Translational Psychiatry
Emerging evidence highlights a critical relationship between gut microbiota and neurocognitive development. Excessive consumption of sugar and other unhealthy dietary factors during early life developmental periods yields changes in the gut microbiom
Autor:
Bo Kyoung Suh, Eunbyul Cho, Jihyun Park, Youngsik Woo, Truong Thi My Nhung, Yeongjun Suh, Yongdo Kwak, Sehyung Cho, Young Un Park, Su Been Lee, Sang Ki Park
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Translational Psychiatry
Translational Psychiatry
Disrupted-in-schizophrenia 1 (DISC1) is a scaffold protein that has been implicated in multiple mental disorders. DISC1 is known to regulate neuronal proliferation, signaling, and intracellular calcium homeostasis, as well as neurodevelopment. Althou
Autor:
Keren Aviel-Shekler, Assaf Malka, Ron Piran, Yara Hamshawi, Kolluru D. Srikanth, Worood Sirhan, Dmitriy Getselter, Evan Elliott
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry
Translational Psychiatry
The etiology of Autism Spectrum Disorders (ASD) includes a strong genetic component and a complicated environmental component. Recent evidence indicates that maternal diabetes, including gestational diabetes, is associated with an increased prevalenc
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-8 (2020)
Translational Psychiatry
Translational Psychiatry
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder of childhood with a strong genetic component. Despite the success of mapping ADHD risk loci, little work has been done to experimentally verify the contribution of these
Autor:
Alexander R. Clark, Jagadesan Sankarasubramani, Steven J. Lisco, Sowmya V. Yelamanchili, Chittibabu Guda, Gurudutt Pendyala, Victoria L. Schaal, Sneh Koul, Peng Xiao, Katherine E. Odegaard, Austin Gowen
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry
Translational Psychiatry
Prescription opioid abuse during and after pregnancy is a rising public health concern. While earlier studies have documented that offspring exposed to opioids in utero have impaired neurodevelopment, a significant knowledge gap remains in comparing
Autor:
Sally J. Rogers, Christine Wu Nordahl, Brianna Heath, Paul Ashwood, Shrujna Patel, Russell C. Dale, Destanie Rose, Adam J. Guastella
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational psychiatry, vol 10, iss 1
Translational Psychiatry
Translational psychiatry, vol 10, iss 1
Translational Psychiatry
Epidemiological and animal research shows that maternal immune activation increases the risk of autism spectrum disorders (ASD) in offspring. Emerging evidence suggests that maternal immune conditions may play a role in the phenotypic expression of n
Autor:
Hala Harony-Nicolas, Carla E. M. Golden, Patrick R. Hof, Victoria X. Wang, Joseph D. Buxbaum, Jason P. Lerch, Yohan Yee
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Translational Psychiatry
Translational Psychiatry
Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene. Neuroanatomical alterations have been reported in both male and female individuals with FXS, yet the morphological underpinnings of these alterati
Autor:
Wei-Wei Li, Jin-Tai Yu, Li-Yong Chen, Wei Xu, Wang-Sheng Jin, Chi Zhu, Yang Xiang, Xiaowei Chen, Zhiming Zhu, Zhian Hu, Xian-Le Bu, Hua-Dong Zhou, Jun Wang, Zhen Wang, Ding-Yuan Tian, Gui-Hua Zeng, Bin-Lu Sun, Yan-Jiang Wang, Yu-Hui Liu, Lin-Lin Shen, Weihong Song
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-12 (2020)
Translational Psychiatry
Translational Psychiatry
Alzheimer’s disease (AD) is the most common cause of age-related dementia and is currently incurable. The failures of current clinical trials and the establishment of modifiable risk factors have shifted the AD intervention from treatment to preven