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pro vyhledávání: 'Lüllmann-Rauch, Renate'
Publikováno v:
Toxicology and applied pharmacology. 114(2)
The purpose of the present cytological and radiochemical study was to investigate whether the immunomodulatory agent 3,6-bis[2-(diethylamino)ethoxy]acridine (CL-90.100) and three congeners induce lysosomal storage of sulfated glycosaminoglycans (sGAG
Publikováno v:
Toxicology and applied pharmacology. 114(2)
In the accompanying paper, four dibasic acridine derivatives were reported to induce lysosomal storage of sulfated glycosaminoglycans (sGAG), i.e., mucopolysaccharidosis, in cultured fibroblast (Handrock et al. Toxicol. Appl. Pharmacol. 114, 1992). T
Autor:
Heinz Lüllmann, Renate Lüllmann-Rauch
Publikováno v:
Toxicology and Applied Pharmacology. 61:138-146
The antiestrogenic drug tamoxifen is an amphiphilic cationic compound and might therefore be suspected to interfere with intralysosomal catabolism of polar lipids as previously observed with several other amphiphilic cationic drugs. Large oral doses
Autor:
Renate Lüllmann-Rauch
Publikováno v:
Toxicology and applied pharmacology. 32(1)
Oral administration of chlorphentermine to rats and guinea pigs caused the formation of abnormal lamellated cytoplasmic inclusions in peripheral blood cells (lymphocytes, neutrophils, monocytes, plasma cells). Short-term experiments in rats revealed
Autor:
Lüllmann-Rauch, Renate
Publikováno v:
In Toxicology and Applied Pharmacology 1975 32(1):32-39