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Autor:
J. Dale Thurman, George L. Wolff, Donna F. Kusewitt, Paul Whittaker, Virginia C. Dunkel, Thomas J. Bucci, Alan Warbritton
Publikováno v:
Toxicologic Pathology. 25:556-564
Genome-related differences to Fe overload between and within rodent species were evaluated in the present study. Male B6C3F, mice, yellow and black C5YSF1 mice, and Fischer 344 (F344) rats were fed AIN-76A diets containing 35 (control), 1,500, 3,500,
Publikováno v:
Toxicologic Pathology. 24:558-563
The effects of increasing dietary levels of Fe on the histopathology of liver, pancreas, spleen, and heart were examined in a rat model for iron overload. Sprague-Dawley rats were fed diets containing 35, 350, 3,500, or 20,000 μg Fe/g, and, after 12