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Autor:
Guillaume Lebreton, Ania Nieszkowska, Corinne Frere, Marc Pineton de Chambrun, Isabelle Martin-Toutain, Guillaume Hékimian, Manon Lejeune, Paul Masi, Juliette Chommeloux, Matthieu Schmidt, Charles-Edouard Luyt, Alain Combes, Nicolas Bréchot, Cyrielle Desnos, Pascal Leprince
Publikováno v:
Thrombosis and Haemostasis. 121:1031-1042
Hemostatic changes induced by extracorporeal membrane oxygenation (ECMO) support have been yet poorly documented in coronavirus-19 (COVID-19) patients who have a baseline complex hypercoagulable state. In this prospective monocentric study of patient
Publikováno v:
Thrombosis and Haemostasis. 122:067-079
Case–control and observational studies have provided a plausible mechanistic link between clot structure and thrombosis. We aimed to identify lifestyle, demographic, biochemical, and genetic factors that influence changes in total fibrinogen concen
Autor:
Gabor G. Toth, Akos Heinemann, Elisabeth Mahla, Thomas Bärnthaler, Florian Prüller, Eva Buschmann, Rufina Schuligoi
Publikováno v:
Thrombosis and Haemostasis. 120:1548-1556
Background For patients treated with dual antiplatelet therapy, standardized drug-specific 3-to-7 day cessation is recommended prior to major surgery to reach sufficient platelet function recovery. Here we investigated the hypothesis that supplementa
Autor:
Nathalie Enjolras, Yesim Dargaud, Sandra Le Quellec, Claude Negrier, Eloïse Perot, Jonathan Girard
Publikováno v:
Thrombosis and Haemostasis. 118:2053-2063
Prophylaxis is currently considered the optimal care for severe haemophilia. For patients and their families one of the major difficulties with prophylaxis is the need for frequent venipunctures. The half-life of standard factor IX (FIX) concentrates
Publikováno v:
Thrombosis and Haemostasis. 117:1486-1497
SummaryDeep-vein thrombosis (DVT) is a common condition that often leads to pulmonary thromboembolism (VTE) and death. The role of prostaglandin-endoperoxide synthase (PTGS)2 in arterial thrombosis has been well established, whereas its impact in ven
Autor:
Jackie F. Price, Kristina F. Standeven, Mark W. J. Strachan, Katie A. Greenhalgh, Paul D. Baxter, Robert F. Storey, Robert A. S. Ariëns, Ramzi A. Ajjan, Peter J. Grant, S. H. Alzahrani
Publikováno v:
Greenhalgh, KA, Strachan, M W, Alzahrani, S H, Baxter, P D, Standeven, KF, Storey, R F, Ariens, R A S, Grant, P J, Price, J & Ajjan, R A 2017, ' BβArg448Lys polymorphism is associated with altered fibrin clot structure and fibrinolysis in type 2 diabetes ', Thrombosis and Haemostasis, vol. 117, no. 2, pp. 295-302 . https://doi.org/10.1160/TH16-07-0554
SummaryBoth type 2 diabetes (T2DM) and Bß448Lys variant of fibrinogen are associated with dense fibrin clots, impaired fibrinolysis and increased cardiovascular risk. It was our objective to investigate whether BßArg448Lys adds to vascular risk by
Publikováno v:
Thrombosis and Haemostasis. 117:479-490
SummaryWe have characterised the pathogenic basis of dysprothrombinaemia in a patient exhibiting paradoxical bleeding and thrombotic defects during pregnancy and postpartum. Genetic analysis revealed that the proband is homozygous for the prothrombin
Publikováno v:
Thrombosis and Haemostasis. 117:543-555
SummaryPlatelet defects due to hyper-responsive GPIbα causing enhanced VWF interaction, counter-intuitively result in bleeding rather than thrombosis. The historical explanation of platelet/VWF clearance fails to explain mechanisms of impaired haemo
Autor:
Marlien Pieters
Publikováno v:
Thrombosis and Haemostasis. 121:408-408
Autor:
Annie Pedersen, Christina Jern, Linnea Lundberg, Staffan Nilsson, Katarina Jood, Petra Redfors, Paul Declerck, Ann Gils
Publikováno v:
Thrombosis and Haemostasis. 116:537-543
SummaryIschaemic stroke patients continue to be at risk for recurrent vascular events for many years. Predictors of long-term prognosis are needed. It was the objective of this study to investigate levels of four haemostatic proteins as long-term pre