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Publikováno v:
Therapeutic Advances in Respiratory Disease
Therapeutic Advances in Respiratory Disease, Vol 14 (2020)
Therapeutic Advances in Respiratory Disease, Vol 14 (2020)
Background: The class III NAD-dependent histone deacetylase (HDAC) sirtuin 1 (SIRT1) is an important regulator of senescence, aging, and inflammation. SIRT1de-acetylates chromatin histones, thereby silencing inflammatory gene transcription. We have r