Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hui K. Gan"'
Autor:
Peter J. Hudson, Pece Kocovski, Ian D. Davis, John Pedersen, Andrew M. Scott, Sze Ting Lee, Scott Williams, Fook-Thean Lee, Graeme O'Keefe, Tim Akhurst, Andrew Weickhardt, Hui K Gan, Michael Paul Wheatcroft, Maggie Oh, Marika Ciprotti, Fiona Scott, Sylvia J. Gong, Linda Mileshkin, Kunthi Pathmaraj, Nancy Guo, Declan G. Murphy, Rodney J. Hicks
Publikováno v:
Theranostics
Through protein engineering and a novel pegylation strategy, a diabody specific to tumor-associated glycoprotein 72 (TAG-72) (PEG-AVP0458) has been created to optimize pharmacokinetics and bioavailability to tumor. We report the preclinical and clini
Autor:
Ingrid Burvenich, Yit Wooi Goh, Sagun Parakh, Hui K Gan, Masakatsu Kotsuma, Andrew M. Scott, Zhanqi Liu, Fook-Thean Lee, Giorgio Senaldi, Graeme O'Keefe, Nancy Guo, Henri Tochon-Danguy, Angela Rigopoulos, Kenji Hirotani, Fiona Scott, Sylvia J. Gong
Publikováno v:
Theranostics
B7-H3 is a transmembrane protein widely expressed in a variety of cancers and has been shown to play a role in anti-tumor immunity. This study aims to develop a molecular imaging probe to identify B7-H3 expression in tumors and to develop 89Zr-DS-557
Autor:
Masakatsu Kotsuma, Henri Tochon-Danguy, Graeme O'Keefe, Ingrid Burvenich, Fook-Thean Lee, Stacey E Rudd, Hui K Gan, Sylvia J. Gong, Nancy Guo, Giorgio Senaldi, Toshiaki Ohtsuka, Andrew M. Scott, Adam C. Parslow, Paul S. Donnelly, Angela Rigopoulos
Publikováno v:
Theranostics
Background: DS-8273a, an anti-human death receptor 5 (DR5) agonistic antibody, has cytotoxic activity against human cancer cells and induces apoptosis after specific binding to DR5. DS-8273a is currently being used in clinical Phase I trials. This st