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Publikováno v:
The Thoracic and Cardiovascular Surgeon. 69:719-722
Cardiopulmonary bypass (CPB) is associated with platelet dysfunction (PD), an important cause of postoperative bleeding. The etiology of PD is not completely understood. We mapped the platelets' function during CPB to determine the etiology of PD. Pl
Autor:
Michal Szlapka, H Hausmann, Martin Scharpenberg, Adrian Bauer, J. Michael Hasenkam, Thomas Eberle, Jan Schaarschmidt
Publikováno v:
Bauer, A, Hausmann, H, Schaarschmidt, J, Szlapka, M, Scharpenberg, M, Eberle, T & Hasenkam, J M 2019, ' Is 300 Seconds ACT Safe and Efficient during MiECC Procedures? ', The Thoracic and Cardiovascular Surgeon, vol. 67, no. 3, pp. 191-202 . https://doi.org/10.1055/s-0037-1609019
Introduction The recommended minimum activated clotting time (ACT) level for cardiopulmonary bypass (CPB) of 480 seconds originated from investigations with bubble oxygenators and uncoated extracorporeal circulation (ECC) systems. Modern minimal inva
Autor:
Hideki Kawai
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 65:392-394
Although the ultrasonic scalpel is known to avoid inadvertent thermal injury to pulmonary parenchyma owing to its lower tip temperature, there are reports suggesting late onset postoperative alveolar air leakage by using it. Herein, a novel method of
Autor:
Christian F Weber, Christian Reyher, Patrick Meybohm, Claire Würfel, Marc Schindewolf, Edelgard Lindhoff-Last, Kai Zacharowski, Anton Moritz
Publikováno v:
The Thoracic and cardiovascular surgeon. 64(6)
Background In patients with autoimmune diseases associated with antiphospholipid antibodies, precise management of anticoagulation during extracorporeal circulation (ECC) is complicated. It was the aim of the present study to determine whether antifa
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 58:148-153
OBJECTIVE: Aim of the study was to discuss a new mechanism underlying the poor graft patency of GSV from diabetic patients and provide a rationale for selecting suitable grafts in diabetic patients. MATERIALS AND METHODS: The discarded matched RA, IM
Publikováno v:
The Thoracic and cardiovascular surgeon. 64(6)
Background Heparin dosage for anticoagulation during cardiopulmonary bypass (CPB) is commonly calculated based on the patient's body weight. The protamine-heparin ratio used for heparin reversal varies widely among institutions (0.7-1.3 mg protamine/
Autor:
V Hraska, Hans-Gerd Wolf, Nicodème Sinzobahamvya, Ehrenfried Schindler, Tomohiro Yamamoto, Boulos Asfour
Publikováno v:
The Thoracic and cardiovascular surgeon. 63(5)
In open heart surgery, heparinization is commonly neutralized using an empirical heparin:protamine ratio ranging between 1:1 and 1:1.5. However, these ratios may result in protamine overdose that should be avoided for its negative side effects on the
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 63
Objectives: To compare routine activated clotting time (ACT) based hemostasis management to individualized heparin management (IHM) in terms of postoperative bleeding, platelet function, and coagulation markers. Methods: 120 CABG patients (≥ 3 dist
Autor:
Y Harder, R. M. Nickels, Michael D. Menger, Hans-Joachim Schäfers, René Schramm, Frank Langer
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 54:506-511
OBJECTIVE Secondary complications involving inflammation limit postoperative results in cardiac surgery. Because heparin-protamine can elicit inflammatory reactions, this study evaluates in vivo whether treatment with heparin-protamine aggravates loc
Autor:
Mustafa Cikirikcioglu, Hasan Sunar, Volkan Yüksel, Cavidan Arar, Enver Duran, Suat Canbaz, Turan Ege
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 52:10-15
Background Protamine has adverse effects on pulmonary gas exchange during the postoperative period. The objective of this study was to investigate the importance of aprotinin and pentoxifylline in preventing the leukocyte sequestration and lung injur