Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Céleste Lebbé"'
Autor:
Céleste Lebbé, Ines Pires da Silva, Irene L.M. Reijers, Megan Lyle, Alexander M. Menzies, Alison Weppler, Shahneen Sandhu, Camille L. Gerard, Matteo S. Carlino, Joanna Mangana, Douglas B. Johnson, Patricio Serra-Bellver, Oliver Klein, James R. Patrinely, Andrew Haydon, Tasnia Ahmed, Olivier Michielin, Khang Nguyen, Claudia Trojaniello, Paul Lorigan, Allison Betof Warner, Dan Stout, Clara Allayous, Christian U. Blank, Paolo A. Ascierto, Lisa Zimmer, Serigne Lo, Georgina V. Long
Publikováno v:
The Lancet Oncology. 22:836-847
Anti-PD-1 therapy (hereafter referred to as anti-PD-1) induces long-term disease control in approximately 30% of patients with metastatic melanoma; however, two-thirds of patients are resistant and will require further treatment. We aimed to determin
Autor:
Piotr Rutkowski, Lars Bastholt, Ralf Gutzmer, Claus Garbe, Virginia Ferraresi, Marta Nyakas, Omid Hamid, Joanna Pikiel, Jean-Jacques Grob, Paolo A. Ascierto, Céleste Lebbé, Caroline Robert, Delphine Hennicken, Vanna Chiarion-Sileni, Michael Smylie, Gabriella Liszkay, Florent Grange, Catriona M. McNeil, Luc Thomas, Dirk Schadendorf, Andrzej Mackiewicz, Michele Del Vecchio, Christoph Hoeller, Carmen Loquai, Michele Maio, Inge Marie Svane, Anila Qureshi, Brigitte Dréno, Ana Arance, Laurent Mortier
Publikováno v:
Ascierto, P A, Del Vecchio, M, Robert, C, Mackiewicz, A, Chiarion-Sileni, V, Arance, A, Lebbe, C, Bastholt, L, Hamid, O, Rutkowski, P, McNeil, C, Garbe, C, Loquai, C, Dreno, B, Thomas, L, Grob, J-J, Liszkay, G, Nyakas, M, Gutzmer, R, Pikiel, J, Grange, F, Hoeller, C, Ferraresi, V, Smylie, M, Schadendorf, D, Mortier, L, Svane, I M, Hennicken, D, Qureshi, A & Maio, M 2017, ' Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma : a randomised, double-blind, multicentre, phase 3 trial ', Lancet Oncology, vol. 18, no. 5, pp. 611-622 . https://doi.org/10.1016/S1470-2045(17)30231-0
Articles Lancet Oncol
Articles Lancet Oncol, 2017, 18 (5), pp.611-622. 〈10.1016/S1470-2045(17)30231-0〉
Lancet Oncology
Lancet Oncology, 2017, 18 (5), pp.611-622. ⟨10.1016/S1470-2045(17)30231-0⟩
Lancet Oncology, Elsevier, 2017, 18 (5), pp.611-622. ⟨10.1016/S1470-2045(17)30231-0⟩
Articles Lancet Oncol
Articles Lancet Oncol, 2017, 18 (5), pp.611-622. 〈10.1016/S1470-2045(17)30231-0〉
Lancet Oncology
Lancet Oncology, 2017, 18 (5), pp.611-622. ⟨10.1016/S1470-2045(17)30231-0⟩
Lancet Oncology, Elsevier, 2017, 18 (5), pp.611-622. ⟨10.1016/S1470-2045(17)30231-0⟩
BACKGROUND: A phase 2 trial suggested increased overall survival and increased incidence of treatment-related grade 3-4 adverse events with ipilimumab 10 mg/kg compared with ipilimumab 3 mg/kg in patients with advanced melanoma. We report a phase 3 t
Autor:
Alexander M.M. Eggermont, Stefan Suciu, Céleste Lebbé, Vanna Chiarion-Sileni, Corneel Coens, Michael Smylie, Alessandro Testori, Omid Hamid, Srividya Kotapati, Andrew Bottomley, Jon M. Richards, Jeffrey S. Weber, Reinhard Dummer, Jean-Jacques Grob, Virginia Ferraresi, Michele Maio, Veerle de Pril, Caroline Robert, Henrik Schmidt, Paolo A. Ascierto, Jedd D. Wolchok
Publikováno v:
Coens, C, Suciu, S, Chiarion-Sileni, V, Grob, J-J, Dummer, R, Wolchok, J D, Schmidt, H, Hamid, O, Robert, C, Ascierto, P A, Richards, J M, Lebbé, C, Ferraresi, V, Smylie, M, Weber, J S, Maio, M, Bottomley, A, Kotapati, S, de Pril, V, Testori, A & Eggermont, A M M 2017, ' Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): secondary outcomes of a multinational, randomised, double-blind, phase 3 trial ', Lancet Oncology, vol. 18, no. 3, pp. 393-403 . https://doi.org/10.1016/S1470-2045(17)30015-3
BACKGROUND:The EORTC 18071 phase 3 trial compared adjuvant ipilimumab with placebo in patients with stage III melanoma. The primary endpoint, recurrence-free survival, was significantly longer in the ipilimumab group than in the placebo group. Invest
Autor:
Paul Nghiem, Kevin M. Chin, Céleste Lebbé, Howard L. Kaufman, Anja von Heydebreck, Isaac Brownell, Shailender Bhatia, Sandra P. D'Angelo, Michele Milella, Jochen H. Lorch, Omid Hamid, Lisa Mahnke, Gerald P. Linette, Kent C. Shih, Jean Marie Cuillerot, Karl D. Lewis, Jeffery S. Russell, Patrick Terheyden
Publikováno v:
The Lancet Oncology. 17:1374-1385
Summary Background Merkel cell carcinoma is a rare, aggressive skin cancer with poor prognosis in patients with advanced disease. Current standard care uses various cytotoxic chemotherapy regimens, but responses are seldom durable. Tumour oncogenesis