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Autor:
Stephan B. Felix, Mario Schiffer, Sigrun Friesecke, Sylvia Stracke, Julia Mayerle, Friedlinde Ernst, Markus M. Lerch, Peter Abel, Jan T. Kielstein, Michael Fiene, Bernhard M W Schmidt, Karin Weissenborn, Kathleen Selleng, Alexander Dressel, Andreas Greinacher
Publikováno v:
The Lancet. 378:1166-1173
Summary Background In May 2011, an outbreak of Shiga toxin-producing enterohaemorrhagic E coli O104:H4 in northern Germany led to a high proportion of patients developing post-enteritis haemolytic uraemic syndrome and thrombotic microangiopathy that
Publikováno v:
The Lancet. 377:1600-1609
Primary biliary cirrhosis is a chronic liver disease characterised by intrahepatic bile-duct destruction, cholestasis, and, in some cases, cirrhosis. Evidence supporting the autoimmune nature of this disorder includes the appearance of highly specifi
Publikováno v:
The Lancet. 365:130-134
Summary Background For microbiological confirmation of diagnosis of pulmonary tuberculosis in young children, sequential gastric lavages are recommended; sputum induction has not been regarded as feasible or useful. We aimed to compare the yield of M
Autor:
Isabelle Cattaneo, François Lemaire, Jean-Claude Lacherade, Laurent Brochard, F. Bruneel, François Hemery, Frédérique Schortgen
Publikováno v:
The Lancet. 357:911-916
Summary Background Hydroxyethylstarch used for volume restoration in brain-dead kidney donors has been associated with impaired kidney function in the transplant recipients. We undertook a multicentre randomised study to assess the frequency of acute
Autor:
Gangjian Qin, Xiumei Gao, Yuan Zhang, Boli Zhang, Guanwei Fan, Yanfen Li, Chuan Li, Jingyuan Mao, Yuhong Huang, Li Li, Hong Wang, Zhen Hu, Xianming Chu, Yingqiang Zhao, Han Zhang, Xiaoying Wang, Lianying Chang, Yi An
Publikováno v:
The Lancet. 388:S34
Background Endothelial progenitor cells (EPCs) derived from bone marrow are associated with the repair of vascular injury by accelerating re-endothelisation, and represent a potential therapeutic target for ischaemic disease. Danhong injection (DHI),
Autor:
Koco Cakalaroski, Josef Hoegel, Christian Guenther, Gerhard M. Gahl, Bolesław Rutkowski, Momir Polenakovic, Wilhelm Gaus, Detlef H. Krieter, Achim Jörres, Clemens Dobis, Ewa Kisielnicka, K Wolfgang Rumpf
Publikováno v:
The Lancet. 354:1337-1341
Summary Background There is controversy as to whether haemodialysismembrane biocompatibility (ie, the potential to activate complement and neutrophils) influences mortality of patients with acute renal failure. We did a prospective randomised multice
Publikováno v:
The Lancet. 354:296-299
Summary Background The effects of oral rehydration solution (ORS) with reduced osmolarity on children with acute watery diarrhoea are known, but little is known about the effects of such ORS on adults with cholera. We aimed to compare the efficacy an
Autor:
Jean-François Delfraissy, Claire Rabian, Yves Levy, E Gomard, Jean-Pierre Aboulker, JG Guillet, L Boumsell, Cécile Goujard, J. A. Gastaut, I Carriere, S Houhou, Jean-Paul Viard, Maxime Seligmann, L Weiss, Eric Oksenhendler, Catherine Capitant
Publikováno v:
The Lancet. 353:1923-1929
Summary Background Intermittent interleukin-2 therapy for HIV-1 by continuous intravenous infusion leads to sustained increase of CD4 T cells. This method of administration is, however, inconvenient and has limiting toxic effects. We did a randomised
Publikováno v:
The Lancet. 353:1689-1694
1The situation is similar for most industrialised western nations, with incidence rates of 18 to 30 new cases per 10 0 000 men placing bladder cancer among the top five cancers in this sex. It is unclear why women are affected a third to a quarter le
Publikováno v:
Lancet (UK), 371(9623), 1486-1488. Elsevier Ltd.
Clostridium difficile is a Gram-positive, anaerobic, spore-producing anaerobe [1] responsible for approximately 50–70% of gastrointestinal infections in hospitalized patients [2, 3]. An episode of C. difficile infection (CDI) is defined as a clinic