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Publikováno v:
The Lancet. 338:725-726
To assess whether chronic pulmonary colonisation with Pseudomonas aeruginosa in cystic fibrosis is preventable, 26 patients who had never received anti-pseudomonas chemotherapy were randomly allocated to groups receiving either no anti-pseudomonas ch
Publikováno v:
The Lancet. 353:846
Publikováno v:
The Lancet. 335:1572-1573
The influence of acetylcysteine, administered at presentation to hospital, on the subsequent clinical course of 100 patients who developed paracetamol-induced fulminant hepatic failure was analysed retrospectively. Mortality was 37% in patients who r
Publikováno v:
The Lancet. 350:1818
Although oral, genital, ocular, and skin lesions are the most frequent manifestations of Behcet’s disease, arthritis (30–50%), thrombophlebitis (50%), and thrombosis (10–15%) may occur. In addition, pulmonary (5–10%), neurological (10–30%),
Publikováno v:
The Lancet. 343:924
Autor:
Richard M. Fox, George Morstyn, Alton Nk, LM Souza, William P. Sheridan, Keech J, Campbell L, Donald Metcalf, Michael D. Green
Publikováno v:
The Lancet. 331:667-672
A phase I/II study of granulocyte colony stimulating factor (G-CSF) was undertaken in patients with advanced malignancy receiving melphalan to determine the granulocyte response, side-effects, and pharmacokinetics. Patients received doses of 1-60 mic
Publikováno v:
The Lancet. 323:821-824
Transiliac bone biopsies carried out on 13 patients with Paget's disease to evaluate the effects of low-dose diphosphonate (disodium etidronate) therapy showed focal osteomalacia in the 9 patients in whom post-therapy specimens were taken through pag
Autor:
T.C. Pearson, G. Wetherley-Mein
Publikováno v:
The Lancet. 312:1219-1222
The relations between the incidence of vascular occlusive episodes and packed-cell volume (P.C.V) and platelet-count in patients with primary proliferative polycythaemia were determined retrospectively in patients treated by venesection with or witho
Publikováno v:
The Lancet. 305:1263-1266
Oral glucose-tolerance test (O.G.T.T.) plasma sugar and insulin levels were measured in 118 newly diagnosed maturity-onset diabetic patients before and after treatment with diet alone for periods of 2 and 6 months. The results of glucose-tolerance te
Autor:
Alex So, Ingvar Bjarnason, T.J. Peters, J.Michael Gumpel, G. Zanelli, Peter H. Williams, A.Jonathan Levi, Barbara M. Ansell
Publikováno v:
The Lancet. 324:1171-1174
The suggestion that the intestinal mucosa may be abnormally permeable and a site of absorption of antigens in rheumatoid arthritis was tested by the use of a 51Cr-EDTA (edetic acid) absorption test. 24 patients with rheumatoid arthritis excreted sign