Zobrazeno 1 - 10
of 111
pro vyhledávání: ''
Autor:
Ian A. Greer
Publikováno v:
The Lancet. 388:2570-2572
Autor:
Swerdlow, Daniel I., Preiss, David, Kuchenbaecker, Karoline B., Holmes, Michael V., Engmann, Jorgen E. L., Shah, Tina, Sofat, Reecha, Stender, Stefan, Johnson, Paul C. D., Scott, Robert A., Leusink, Maarten, Verweij, Niek, Sharp, Stephen J., Guo, Yiran, Giambartolomei, Claudia, Chung, Christina, Peasey, Anne, Amuzu, Antoinette, Li, KaWah, Palmen, Jutta, Howard, Philip, Cooper, Jackie A., Drenos, Fotios, Lowe, Gordon, Gallacher, John, Stewart, Marlene C. W., Tzoulaki, Ioanna, Buxbaum, Sarah G., van der A, Daphne L., Forouhi, Nita G., Onland-Moret, N. Charlotte, van der Schouw, Yvonne T., Hubacek, Jaroslav A., Kubinova, Ruzena, Baceviciene, Migle, Tamosiunas, Abdonas, Pajak, Andrzej, Topor-Madry, Roman, Stepaniak, Urszula, Malyutina, Sofia, Baldassarre, Damiano, Sennblad, Bengt, Tremoli, Elena, de Faire, Ulf, Veglia, Fabrizio, Ford, Ian, Wouter Jukema, J., Westendorp, Rudi G. J., de Borst, Gert Jan, de Jong, Pim A., Algra, Ale, Spiering, Wilko, H Maitland-van der Zee, Anke H., Klungel, Olaf H., de Boer, Anthonius, Doevendans, Pieter A., Eaton, Charles B., Robinson, Jennifer G., Duggan, David, DIAGRAM Consortium, MAGIC Consortium, InterAct Consortium, Kjekshus, John, Downs, John R., Gotto, Antonio M., Keech, Anthony C., Marchioli, Roberto, Tognoni, Gianni, Sever, Peter S., Poulter, Neil R., Waters, David D., Pedersen, Terje R., Amarenco, Pierre, Nakamura, Haruo, McMurray, John J. V., Lewsey, James D., Chasman, Daniel I., Ridker, Paul M., Maggioni, Aldo P., Tavazzi, Luigi, Ray, Kausik K., Kondapally Seshasai, Sreenivasa Rao, Manson, JoAnn E., Price, Jackie F., Whincup, Peter H., Morris, Richard W., Lawlor, Debbie A., Smith, George Davey, Ben-Shlomo, Yoav, Schreiner, Pamela J., Fornage, Myriam, Siscovick, David S., Cushman, Mary, Kumari, Meena, Wareham, Nick J., Verschuren, W. M. Monique, Redline, Susan, Patel, Sanjay R., Whittaker, John C., Hamsten, Anders, Delaney, Joseph A., Dale, Caroline, Gaunt, Tom R., Wong, Andrew, Kuh, Diana, Hardy, Rebecca, Kathiresan, Sekar, Castillo, Berta A., van der Harst, Pim, Brunner, Eric J., Tybjaerg-Hansen, Anne, Marmot, Michael G., Krauss, Ronald M., Tsai, Michael, Coresh, Josef, Hoogeveen, Ronald C., Psaty, Bruce M., Lange, Leslie A., Hakonarson, Hakon, Dudbridge, Frank, Humphries, Steve E., Talmud, Philippa J., Kivimäki, Mika, Timpson, Nicholas J., Langenberg, Claudia, Asselbergs, Folkert W., Voevoda, Mikhail, Bobak, Martin, Pikhart, Hynek, Wilson, James G., Reiner, Alex P., Keating, Brendan J., Hingorani, Aroon D., Sattar, Naveed, Li, Yun R.
Publikováno v:
The Lancet, 385(9965), 351-361. ELSEVIER SCIENCE INC
Swerdlow, D I, Preiss, D, Kuchenbaecker, K B, Holmes, M V, Engmann, J E L, Shah, T, Sofat, R, Stender, S, Johnson, P C D, Scott, R A, Leusink, M, Verweij, N, Sharp, S J, Guo, Y, Giambartolomei, C, Chung, C, Peasey, A, Amuzu, A, Li, K, Palmen, J, Howard, P, Cooper, J A, Drenos, F, Li, Y R, Lowe, G, Gallacher, J, Stewart, M C W, Tzoulaki, I, Buxbaum, S G, van der A, D L, Forouhi, N G, Onland-Moret, N C, van der Schouw, Y T, Schnabel, R B, Hubacek, J A, Kubinova, R, Baceviciene, M, Tamosiunas, A, Pajak, A, Topor-Madry, R, Stepaniak, U, Malyutina, S, Baldassarre, D, Sennblad, B, Tremoli, E, de Faire, U, Veglia, F, Ford, I, Jukema, J W & Price, J F 2015, ' HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials ', The Lancet, vol. 385, no. 9965, pp. 351-361 . https://doi.org/10.1016/S0140-6736(14)61183-1
Lancet, 385(9965), 351-361
The Lancet. Lancet Publishing Group
The Lancet, 385(9965), 351. Elsevier Limited
Lancet
Swerdlow, D I, Preiss, D, Kuchenbaecker, K B, Holmes, M V, Engmann, J E L, Shah, T, Sofat, R, Stender, S, Johnson, P C D, Scott, R A, Leusink, M, Verweij, N, Sharp, S J, Guo, Y, Giambartolomei, C, Chung, C, Peasey, A, Amuzu, A, Li, K, Palmen, J, Howard, P, Cooper, J A, Drenos, F, Li, Y R, Lowe, G, Gallacher, J, Stewart, M C W, Tzoulaki, I, Buxbaum, S G, van der A, D L, Forouhi, N G, Onland-Moret, N C, van der Schouw, Y T, Schnabel, R B, Hubacek, J A, Kubinova, R, Baceviciene, M, Tamosiunas, A, Pajak, A, Topor-Madry, R, Stepaniak, U, Malyutina, S, Baldassarre, D, Sennblad, B, Tremoli, E, de Faire, U, Veglia, F, Ford, I, Jukema, J W & Price, J F 2015, ' HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials ', The Lancet, vol. 385, no. 9965, pp. 351-361 . https://doi.org/10.1016/S0140-6736(14)61183-1
Lancet, 385(9965), 351-361
The Lancet. Lancet Publishing Group
The Lancet, 385(9965), 351. Elsevier Limited
Lancet
Background: Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the intended drug target.Methods: We use
Publikováno v:
The Lancet. 391:2501-2502
Autor:
Michael E, Wechsler, Susan J, Kunselman, Vernon M, Chinchilli, Eugene, Bleecker, Homer A, Boushey, William J, Calhoun, Bill T, Ameredes, Mario, Castro, Timothy J, Craig, Loren, Denlinger, John V, Fahy, Nizar, Jarjour, Shamsah, Kazani, Sophia, Kim, Monica, Kraft, Stephen C, Lazarus, Robert F, Lemanske, Amy, Markezich, Richard J, Martin, Perdita, Permaul, Stephen P, Peters, Joe, Ramsdell, Christine A, Sorkness, E Rand, Sutherland, Stanley J, Szefler, Michael J, Walter, Stephen I, Wasserman, Elliot, Israel, Cheryl, Wilmoth
Publikováno v:
The Lancet. 374:1754-1764
Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than
Autor:
Ka Fai To, Jean Woo, Cynthia Chan, Francis K.L. Chan, Elsie Hui, Joseph J.Y. Sung, Henry Lik-Yuen Chan, Man Yee Yung, Wai K. Leung, Yui Hui, Justin C.Y. Wu, Timothy Kwok
Publikováno v:
The Lancet. 359:9-13
Summary Background Whether Helicobacter pylori increases the risk of ulcers in patients taking non-steroidal anti-inflammatory drugs (NSAIDs) is controversial. We hypothesised that eradication of H pylori infection would reduce the risk of ulcers for
Autor:
Jeffrey I. Weitz, Sonia S. Anand, Klas Malmberg, Jeffrey S. Ginsberg, John W. Eikelboom, Salim Yusuf
Publikováno v:
The Lancet. 355:1936-1942
In acute coronary syndrome without ST elevation, the role of unfractionated and low-molecular-weight heparin in aspirin-treated patients remains unclear, and there is conflicting evidence regarding the efficacy and safety of low-molecular-weight hepa
Autor:
Otmar Carewicz, A. Rode, Penelope Ward, Fred Y. Aoki, C. H. Mercier, Karl G. Nicholson, Sylvie Trottier, N. Kinnersley, Albert D. M. E. Osterhaus
Publikováno v:
Lancet (UK), 355, 1845-1850. Elsevier Ltd.
Summary Background Use of some antiviral drugs for influenza infection is limited by potential rapid emergence of resistance. We studied the efficacy and safety of oseltamivir, the oral prodrug of the neuraminidase inhibitor GS4071, in adults with na
Autor:
A. Filipowicz-Sosnowska, Christopher J. Hawkey, K. R. W. Gillon, Zsolt Tulassay, L. Szczepanski, C. M. Wason, C. J. Van Rensburg, Angel Lanas, R. A. Peacock
Publikováno v:
The Lancet. 352:1016-1021
Summary Background The effect of Helicobacter pylori in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) is unclear. We investigated the effects of H pylori eradication in patients with current or previous peptic ulceration, dyspepsi
Autor:
Bernd Hoppe, Ernst Rietschel, Ammon B. Peck, Sabine Bromme, Klaus Tenbrock, Albrecht Hesse, Harmeet Sidhu
Publikováno v:
The Lancet. 352:1026-1029
Summary Background Patients with cystic fibrosis have an increased risk of hyperoxaluria, and of subsequent nephrocalcinosis and calcium-oxalate urolithiasis. Oxalate homoeostasis is controlled, in part, by the intestinal bacterium, Oxalobacter formi
Publikováno v:
The Lancet. 350:1590-1593
Summary Background Inflammatory and coagulation processes are both affected in meningococcaemia. Severe acquired protein-C deficiency in meningococcaemia is usually associated with substantial mortality; in survivors, skin grafts, amputation, and end