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of 5
pro vyhledávání: '"Alan R. Shuldiner"'
Autor:
Coleen M. Damcott, Braxton D. Mitchell, Laura M. Yerges-Armstrong, Joanne E. Curran, Sumbul Chai, John Blangero, Alan R. Shuldiner, Jeffery R. O'Connell
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 71:1295-1299
Although there is compelling evidence for a genetic contribution to longevity, identification of specific genes that robustly associate with longevity has been a challenge. In order to identify longevity-enhancing genes, we measured differential gene
Autor:
Alan R. Shuldiner, Huber R. Warner, Robert N. Butler, Richard L. Sprott, Steven N. Austad, Anna M. McCormick, Nir Barzilai, Pamela L. Larsen, Andreas Braun, Thomas T. Perls, Stephen L. Helfand
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 58:B581-B584
International Longevity Center-USA, New York. University of Idaho, Moscow. Albert Einstein College of Medicine, New York. Sequenom, Inc., San Diego, California. University of Connecticut Health Center, Farmington. University of California, Los Angele
Autor:
Alan R. Shuldiner, Nir Barzilai
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 56:M83-M87
Over the last 30 years, a number of genetic and environmental factors that lead to decreased length of life have been identified. Unfortunately, much less progress has been achieved in identifying genes associated with longevity that protect from com
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :B308-B315
A cDNA termed reg (for regenerating gene) has been isolated from a rat pancreatic DNA library. Reg expression has been shown to correlate with changes in beta cell mass and function. This finding has been recently challenged by studies showing a non-
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :B331-B336
Aging is an etiologic factor in non-insulin-dependent diabetes mellitus. While the effect of aging on insulin secretion has been described by several classic studies, the characterization of the molecular basis of beta-cell abnormalities is still und