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Autor:
Thiago R. Araujo, Israelle N. Freitas, Joel Alves da Silva Junior, Antonio C. Boschero, Kênia Moreno de Oliveira, Rosane Aparecida Ribeiro, Julia R. Clarke, Gésily de Souza Aguiar, Cremilda do Amaral Roso de Oliveira, Helene Nara Henriques, Maria Lúcia Bonfleur, Jean Franciesco Vettorazzi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 190:54-63
Oral contraception is the most commonly used interventional method in the world. However, several women employ the continuous use of these hormones to avoid pre- and menstruation discomforts. Some studies indicate that oral contraceptives are associa
Autor:
Cristina Parrado-Fernandez, Paula Merino-Serrais, Silvia Maioli, Raúl Loera-Valencia, Julen Goikolea
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the complete pathogenesis of the disease is still unknown. High leve
Autor:
Brian G. Keevil, Jo Adaway
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 190:207-211
Testosterone (T) is strongly bound to sex hormone binding globulin and measurement of free T may be more appropriate than measuring total serum T, according to the free hormone theory. This view remains controversial and it has its detractors who cla
5-Lipoxygenase (ALOX5): Genetic susceptibility to type 2 diabetes and vitamin D effects on monocytes
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 187:52-57
The arachidonate 5-lipoxygenase (ALOX5) pathway has been implicated in chronic inflammatory disease which may be influenced by vitamin D due to vitamin D response elements (VDRE). We investigated an ALOX5 polymorphism (rs4987105) in patients with typ
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 185:225-236
Visfatin is an adipokine which has an endocrine effect on reproductive functions and regulates ovarian steroidogenesis. There is scant information about the expression, regulation, and functions of visfatin in the mammalian uterus. The present study
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 185:137-141
Angiotensin 1-7 (Ang 1-7), which is a protein cleaved from angiotensin II (A-II), binds to the MAS receptor. Ang 1-7 has been demonstrated to exert protective effects against A-II-mediated cardiac, atherosclerotic, and renal damages. The aims of our
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 215:106024
Aldosterone, the main physiological mineralocorticoid in humans and other terrestrial vertebrates, first appears in lungfish, which are lobe-finned fish that are forerunners of terrestrial vertebrates. Aldosterone activation of the MR regulates inter
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 181:109-124
A non-linear mechanistic model for the distribution of cortisol in plasma on free and bound forms is proposed. The influence of progesterone, testosterone and neutrophil elastase on the cortisol distribution in the blood is investigated. The activity
Autor:
Tomi-Pekka Tuomainen, Sabine Seuter, Tarja Nurmi, Jyrki K. Virtanen, Carsten Carlberg, Antonio Neme
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 180:142-148
In vitro cell culture studies showed that the hormonal form of vitamin D3, 1α,25-dihydroxyvitamin D3, significantly (p
Autor:
Mohammed S. Razzaque
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 180:81-86
Vitamin D is a fat-soluble hormone that has endocrine, paracrine and autocrine functions. Consumption of vitamin D-supplemented food & drugs have increased significantly in the last couple of decades due to campaign and awareness programs. Despite su