Zobrazeno 1 - 10
of 925
pro vyhledávání: ''
Autor:
Alexandre Chagas Santana, Raul C. Maranhão, Rafael Pepineli, Irene L. Noronha, Filipe M. O. Silva, Noedir Antônio Groppo Stolf, Thauany M Tavoni
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
ObjectivesThe aim of this study was to test whether lipid core nanoparticles loaded with paclitaxel (LDE-PTX) protect rat aortic allograft from immunological damage.MethodsFisher and Lewis rats were used differing in minor histocompatibility loci. Si
Autor:
Nasser Hadal Alotaibi, Muhammad Saleem, Muhammad Naveed Mushtaq, Khalid Saad Alharbi, Syed Nasir Abbas Bukhari, Amna Batool, Alamgeer
Publikováno v:
The Journal of pharmacy and pharmacology. 74(4)
Objectives Polygnum hydropiper L (Polygonaceae) is commonly known as smart weed. This study was designed to assess the effect of aqueous methanolic extract of P. hydropiper on oxidative stress and metabolic changes in fructose-induced hypertensive ra
Autor:
Chunxiao Ye, Qing Ding, Xia Zhan, Bin Lv, Jun Peng, Xixiao Yang, Shulong Wu, Tianrong Xun, Congyan Chen, Bin Liu, Liqian Mo, Xiaokang Wang
Publikováno v:
The Journal of pharmacy and pharmacology. 73(8)
Objectives The aim of the study was to explore the effect of total glucosides of paeony (TGP) and Tripterygium wilfordii polyglycosides (TWP) on erythrocyte methotrexate polyglutamates (MTXPGs), the metabolites of methotrexate (MTX). Methods An ultra
Publikováno v:
The Journal of pharmacy and pharmacology. 73(8)
Objective The aim of this study was to delineate the mechanisms of action of the plant Eucalyptus citriodora used traditionally for the treatment of type 2 diabetes. Methods Insulin secretion and signal transduction were measured using clonal pancrea
Autor:
Priscila de Souza, Luisa Mota da Silva, Valdir Cechinel Filho, Thaise Boeing, Luísa Nathália Bolda Mariano, Rivaldo Niero
Publikováno v:
The Journal of pharmacy and pharmacology. 73(5)
Objectives This study investigated the prolonged diuretic and renal effects of 1,3,5,6- tetrahydroxyxanthone (THX) in rats. Methods Normotensive (NTR) and hypertensive rats (SHR) received orally the treatment with THX, hydrochlorothiazide or vehicle
Publikováno v:
The Journal of pharmacy and pharmacology. 73(11)
Objectives Considering the complementary nature of signalling mechanisms and the therapeutic effects of nebivolol, a β1-adrenoreceptor antagonist, and valsartan, an angiotensin receptor blocker (ARB), here we aimed to investigate whether nebivolol/v
Publikováno v:
The Journal of pharmacy and pharmacology. 74(4)
Objectives Diabetes mellitus (DM) is a chronic disease associated with serious complications, including male infertility. Umbelliferone (UMB) is a coumarin with promising antioxidant, anti-inflammatory and other beneficial effects. This study investi
Autor:
Kazuhiko Arimori, Keishi Yamasaki, Muneaki Hidaka, Yumiko Furuya, Hiroshige Ono, Yohei Kawano
Publikováno v:
The Journal of pharmacy and pharmacology. 73(2)
Objectives Irinotecan is a widely intravenously used drug for the treatment of certain types of solid tumours. The oral administration of irinotecan has recently been recognized as being a more effective method for the treatment than intravenous admi
Autor:
Layany Carolyny Mourão Mulvaney, Vera Lúcia Garcia, Alice M. S. Rodrigues, Francisco Humberto Xavier-Júnior, Didier Stien, Silmara Marques Allegretti
Publikováno v:
Journal of Pharmacy and Pharmacology
Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2021, 73, pp.377-387. ⟨10.1093/jpp/rgaa030⟩
Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2021, 73, pp.377-387. ⟨10.1093/jpp/rgaa030⟩
Objectives To evaluate the antibacterial, antifungal and anthelmintic activities of the ethanolic extract (EEMz), fractions (LPFMz and HPFMz) and compounds isolated from the leaves of Manilkara zapota L. P. Royen. Methods Extract and fractions were p
Autor:
Mahsa Kaveh, Nama Mohammadian Roshan, Farzaneh Shakeri, Mohammad Hossein Boskabady, Ramin Rezaee
Publikováno v:
The Journal of pharmacy and pharmacology. 71(7)
Objectives Effect of alpha-linolenic acid (ALA) against ovalbumin (OVA)-induced inflammation, oxidant/antioxidant imbalance and pathological features was examined in rat. Methods Total and differential WBC count and oxidant/antioxidant levels in BALF