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Ezetimibe Reduces Plant Sterol Accumulation and Favorably Increases Platelet Count in Sitosterolemia
Autor:
Rgia A. Othman, David Mymin, Peter B. Jones, Robert D. Steiner, Louise S. Merkens, Semone B. Myrie, Jean Baptiste Roullet
Publikováno v:
The Journal of Pediatrics. 166:125-131
To assess if ezetimibe (EZE), a sterol-absorption inhibitor, improves platelet (PLT) count and size relative to its effect on plasma plant sterol (PS) in patients with sitosterolemia (STSL).Patients with STSL (5 males, 3 females, 16-56 years of age)
Publikováno v:
The Journal of Pediatrics. 136:370-375
To validate a scoring system to assess the severity of renal lesions and to correlate histology with clinical findings. We also examined the efficacy of treatment with prednisone (1 to 2 mg/kg/d) and azathioprine (1 to 2 mg/kg/d) for severe Henoch-Sc
Publikováno v:
The Journal of pediatrics. 161(4)
Figure 2. Newborn with flaccid bullae and denuded skin areas on her extremities. A 1-hour-old female patient was referred with skin erosions on her extremities. The patient’s mother was a 33-year-old, otherwise-healthy woman with a 6-year history o
Publikováno v:
The Journal of Pediatrics. 124:215-219
The objectives of this study were to quantify the amount of blood required to suppress synthesis of hemoglobin S (HbS) in patients with hemoglobin SS on a long-term transfusion regimen and to evaluate factors that might contribute to variations in tr
Publikováno v:
The Journal of pediatrics. 159(1)
Objective To determine the effectiveness of sequential therapy compared with standard triple therapy for Helicobacter pylori eradication in children. Study design In 107 children with H pylori infection confirmed with 2 of 3 tests ( 13 C-urea breath
Publikováno v:
The Journal of Pediatrics. 119:578-585
Ninety-four children with febrile urinary tract infection were studie prospectively to determine the relationship between vesicoureteral reflux, P-fimbriated Escherichia coli , and acute pyelonephritis, and to evaluate the diagnostic reliability of c
Autor:
Antonio Balsamo, Alessandro Cicognani, Milva Orquidea Bal, Silvia Sansavini, Enrico De Cristofaro, Monia Gennari, L. F. Orsini, Alessandra Cassio
Publikováno v:
The Journal of pediatrics. 149(4)
Objective To evaluate the adult reproductive outcome in girls with early puberty who participated in a previous random study. Study design A total of 22 subjects treated with triptorelin 3.75 mg every 4 weeks (group 1), 18 subjects not treated (group
Publikováno v:
The Journal of pediatrics. 146(2)
Objectives The aim of the study was to determine if a new conductivity measuring sweat test system (Nanoduct) could reliably identify patients with cystic fibrosis (CF) and differentiate them from healthy subjects. Study design On the same day and in
Autor:
Peadar G. Noone, Darin G. Bosworth, Pierre M. Barker, Michael R. Knowles, Kevin W Southern, Vicky A. LeGrys
Publikováno v:
The Journal of pediatrics. 139(3)
Objective: To establish a method for measuring nasal transepithelial potential difference (PD) in infants. Study design: A modified infant method (smaller catheter size, reduced flow rates, and shorter protocol time) was compared with an established
Publikováno v:
The Journal of pediatrics. 137(6)
Objective: Sweat production is stimulated by both cholinergic and β-adrenergic pathways in the sweat gland secretory coil. β-Adrenergic pathway–mediated sweating is absent in cystic fibrosis (CF) because cyclic adenosine monophosphate (cAMP)–me