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Ezetimibe Reduces Plant Sterol Accumulation and Favorably Increases Platelet Count in Sitosterolemia
Autor:
Rgia A. Othman, David Mymin, Peter B. Jones, Robert D. Steiner, Louise S. Merkens, Semone B. Myrie, Jean Baptiste Roullet
Publikováno v:
The Journal of Pediatrics. 166:125-131
To assess if ezetimibe (EZE), a sterol-absorption inhibitor, improves platelet (PLT) count and size relative to its effect on plasma plant sterol (PS) in patients with sitosterolemia (STSL).Patients with STSL (5 males, 3 females, 16-56 years of age)
Publikováno v:
The Journal of Pediatrics. 124:215-219
The objectives of this study were to quantify the amount of blood required to suppress synthesis of hemoglobin S (HbS) in patients with hemoglobin SS on a long-term transfusion regimen and to evaluate factors that might contribute to variations in tr
Publikováno v:
The Journal of Pediatrics. 105:793-798
Erythropoietin, hemoglobin, hematocrit, oxygen affinity (P50), and reticulocyte counts were measured weekly starting at 1 week of age in 10 very-low-birth-weight infants and on a single occasion in 15 healthy men. In the adults, "available oxygen" (d
Autor:
Stanley M. Higashino, Bruce G. Nickerson, Michelle Minor, Elliott Vichinsky, Bertram H. Lubin, Klara Kleman, Rukmani Pennathur-Das
Publikováno v:
The Journal of pediatrics. 105(1)
An increase in hemoglobin concentration characterizes the normal compensatory response to chronic tissue hypoxia. We observed no such increase in 42 chronically hypoxic patients with cystic fibrosis, in whom the mean concentration was 12.6 gm/dl; one