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Publikováno v:
The Journal of Nutrition. 142:1590-1595
Coadministration of retinoic acid (RA) and polyinosinic acid:polycytidylic acid (PIC) has been shown to cooperatively enhance the anti–tetanus toxoid (anti-TT) vaccine response in adult mice. Germinal center formation in the spleen is critical for
Publikováno v:
The Journal of Nutrition. 139:1067-1072
Vitamin A (VA), all-trans-retinol (at-ROL), and its derivative, all-trans-retinoic acid (at-RA), are required for neuron development. The effects of these retinoids are dependent upon the nutritional status of the rat and tissue-specific dynamics of
Publikováno v:
The Journal of Nutrition. 138:2337-2341
Matrix gamma-carboxyglutamic acid protein (MGP), a vitamin K-dependent protein, is involved in regulation of tissue calcification. We previously reported that 9-cis retinoic acid (RA) mitigates 1alpha,25-dihydroxycholecalciferol [1,25(OH)(2)D3]-induc
Autor:
Nan Qian Li, A. Catharine Ross
Publikováno v:
The Journal of Nutrition. 137:2371-2376
The lungs require an adequate supply of vitamin A for normal embryonic development, postnatal maturation, and maintenance and repair during adult life. We have previously shown that a nutrient-metabolite combination of vitamin A admixed with a small
Autor:
Nan Qian Li, A. Catharine Ross
Publikováno v:
The Journal of Nutrition. 137:2213-2218
Although it is understood that plasma retinol concentration is not proportional to the concentration of vitamin A stored in liver, plasma retinol still is often used as an indicator of vitamin A status. An aim of vitamin A supplementation strategies
Autor:
Xiang-Dong Wang, Kang-Quan Hu, Norman I. Krinsky, Robert M. Russell, Pankaj Prakash, Chun Liu
Publikováno v:
The Journal of Nutrition. 134:667-673
Low-dose beta-carotene (BC) supplementation, such as would be provided by daily consumption of approximately 5-9 servings of fruits and vegetables, has no apparent detrimental effects, but rather appears to have a protective effect against cigarette
Autor:
Hector F. DeLuca, Cynthia M. Rohde
Publikováno v:
The Journal of Nutrition. 133:777-783
The mechanism by which all-trans retinoic acid (ATRA) induces bone resorption is unknown. However, an interaction between vitamin A and vitamin D has been established. In fact, although the mechanism is still unclear, vitamin A has been shown to be a
Publikováno v:
The Journal of Nutrition. 132:3809S-3813S
Retinoids have been shown to inhibit the growth of many human tumor cells. Although the exact molecular mechanism of retinoid-mediated growth suppression remains known, the importance of the retinoic acid receptors (RARs) and retinoid X receptors (RX
Autor:
A. Catharine Ross, Reza Zolfaghari
Publikováno v:
The Journal of Nutrition. 132:1160-1164
Lecithin:retinol acyltransferase (LRAT), a retinol esterifying enzyme, plays a major role in the metabolism and storage of vitamin A in several animal tissues. Groups of vitamin A (VA)-adequate (control) and VA-deficient rats were treated with vehicl
Publikováno v:
The Journal of Nutrition. 131:3197-3203
The objectives of the present study were to compare the bioavailability of vitamin A from liver paste and from a vitamin A supplement at three nutritionally relevant levels of intake, and to estimate levels of "safe" intake based on concentrations of