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pro vyhledávání: '"Mary C. Olmstead"'
Autor:
Christopher Cook, Catherine M. Cahill, Anna M.W. Taylor, Niall P. Murphy, Alison J. Taylor, Annie Castonguay, Atefeh Ghogha, Christopher J. Evans, Yves De Koninck, Mary C. Olmstead, Lihua Xue
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(22)
Chronic pain attenuates midbrain dopamine (DA) transmission, as evidenced by a decrease in opioid-evoked DA release in the ventral striatum, suggesting that the occurrence of chronic pain impairs reward-related behaviors. However, mechanisms by which
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 18(13)
The pedunculopontine tegmental nucleus (PPTg) is believed to play important roles in reward and learning. We examined the effect of PPTg lesions (0.5 μl of 0.1mNMDA injected bilaterally over 10 min) on the learning of an operant response for opiate