Zobrazeno 1 - 10
of 75
pro vyhledávání: ''
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(17)
Kainate receptors containing the GluK1 subunit have an impact on excitatory and inhibitory neurotransmission in brain regions, such as the amygdala and hippocampus, which are relevant to seizures and epilepsy. Here we used 2-amino-3-(3-hydroxy-5-tert
Autor:
James E. Goldman, Angeliki Mela
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(18)
Mechanisms that regulate oligodendrocyte (OL) precursor migration and differentiation are important in normal development and in demyelinating/remyelinating conditions. We previously found that the tetraspanin CD82 is far more highly expressed in O4+
Autor:
Xian Xiao, Jin Cheng, Xiang Wang, Ye Yu, Wei Guang Li, Tian Le Xu, Michael X. Zhu, Zhong Peng, Wei-Zheng Zeng
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(10)
Tissue acidosis and inflammatory mediators play critical roles in inflammatory pain. Extracellular acidosis activates acid-sensing ion channels (ASICs), which have emerged as key sensors for extracellular protons in the central and peripheral nervous
Autor:
Iness Charfi, Nicolas Audet, Mohammad Amraei, Anne Julie Chabot-Doré, Graciela Piñeyro, Laura S. Stone, Ouissame Mnie-Filali, Magali Millecamps
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(14)
Opioid tendency to generate analgesic tolerance has been previously linked to biased internalization. Here, we assessed an alternative possibility; whether tolerance of delta opioid receptor agonists (DORs) could be related to agonist-specific recycl
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(5)
Two motivational processes affect choice between actions: (1) changes in the reward value of the goal or outcome of an action and (2) changes in the predicted value of an action based on outcome-related stimuli. Here, we evaluated the role of μ-opio
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(37)
Over the past few years, δ-opioid receptors (DOPRs) and μ-opioid receptors (MOPRs) have been shown to interact with each other. We have previously seen that expression of MOPR is essential for morphine and inflammation to potentiate the analgesic p
Autor:
Eric J. Nestler, Ming-Hu Han, Scott Edwards, Kimberly N. Whisler, Diana Simmons, Erin B. Larson, Kwang H. Choi, Amelia J. Eisch, Zia Ur Rahman, Lisa M. Monteggia, David W. Self, Danielle Graham, Rachael L. Neve, Allyson K. Friedman, Jessica J. Walsh
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(21)
Chronic cocaine use produces numerous biological changes in brain, but relatively few are functionally associated with cocaine reinforcement. Here we show that daily intravenous cocaine self-administration, but not passive cocaine administration, ind
Autor:
Joaquim A. Ribeiro, Daniela B. Pereira, Ana M. Sebastião, Vasco C. Sousa, Natália Assaife-Lopes, Moses V. Chao
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Copyright © 2010 the authors
Brain-derived neurotrophic factor (BDNF) signaling is critical for neuronal development and transmission. Recruitment of TrkB receptors to lipid rafts has been hown to be necessary for the activation of specific sig
Brain-derived neurotrophic factor (BDNF) signaling is critical for neuronal development and transmission. Recruitment of TrkB receptors to lipid rafts has been hown to be necessary for the activation of specific sig
Autor:
Adrianne G. Huxtable, John J. Greer, Sebastian Q Vrouwe, Betty Y. Poon, Gregory D. Funk, Jennifer D. Zwicker, Silvia Pagliardini
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(47)
ATP released during hypoxia from the ventrolateral medulla activates purinergic receptors (P2Rs) to attenuate the secondary hypoxic depression of breathing by a mechanism that likely involves a P2Y1R-mediated excitation of preBötzinger complex (preB
Autor:
Allan I. Levey, D. H. Snyder, Zixiu Xiang, James J. Doherty, Thomas M. Bridges, Jack Philip Kennedy, Albert A. Davis, Edward P. Christian, Jana K. Shirey, Ashley E. Brady, Michelle M. Nicolle, Satyawan Jadhav, Usha N. Menon, P.J. Conn, Michael C. Quirk, M. L. Watson, J. J. Lah, Paulianda J. Jones, Craig W. Lindsley
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(45)
M1muscarinic acetylcholine receptors (mAChRs) may represent a viable target for treatment of disorders involving impaired cognitive function. However, a major limitation to testing this hypothesis has been a lack of highly selective ligands for indiv