Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Larisa V. Gubareva"'
Autor:
Larisa V. Gubareva, Juan A. De La Cruz, Anton Chesnokov, Mira C. Patel, Ha T. Nguyen, Lori Lollis, Vasiliy P. Mishin, David E. Wentworth, Vivien G. Dugan
Publikováno v:
J Infect Dis
Susceptibility of influenza A viruses to baloxavir can be affected by changes at amino acid residue 38 in the polymerase acidic (PA) protein. Information on replicative fitness of PA-I38-substituted viruses remains sparse. We demonstrated that substi
Autor:
Mikhail Matrosovich, Robert G. Webster, Richard C. Bethell, Malcolm K. Brenner, Larisa V. Gubareva
Publikováno v:
The Journal of Infectious Diseases. 178:1257-1262
Zanamivir, a neuraminidase inhibitor, has shown promise as a drug to control influenza. During prolonged treatment with zanamivir, a mutant virus was isolated from an immunocompromised child infected with influenza B virus. A hemagglutinin mutation (
Publikováno v:
The Journal of infectious diseases. 172(1)
A Vero cell line was investigated as a suitable host system for primary isolation and cultivation of influenza A viruses. The efficiency of primary isolation for currently circulating (H3N2) strains was similar in Vero and MDCK cells. Of 72 egg-adapt