Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Christopher P. Klimko, Chris W Schellhase, Nancy A. Twenhafel, Jeremy A. Miller, Christopher K. Cote, Donald J. Chabot, John R. Barr, Susham S. Ingavale, Mary E. Wright, Nicholas J. Vietri, Adrian R. Woolfitt, David P Fetterer, Anne E. Boyer, Brandon Somerville, Arthur M. Friedlander, Steven A. Tobery
Publikováno v:
J Infect Dis
Background Inhalational anthrax is rare and clinical experience limited. Expert guidelines recommend treatment with combination antibiotics including protein synthesis-inhibitors to decrease toxin production and increase survival, although evidence i
Autor:
Joao Pedro Lopes, Michael J. Peluso, Hsi-en Ho, Michael P. Mullen, Chen He, Judith A. Aberg, Michael M. Gaisa, Colton Margus, Georgina Osorio
Publikováno v:
The Journal of Infectious Diseases
The Journal of infectious diseases, vol 223, iss 3
The Journal of infectious diseases, vol 223, iss 3
We performed a retrospective study of coronavirus disease 2019 (COVID-19) in people with human immunodeficiency virus (PWH). PWH with COVID-19 demonstrated severe lymphopenia and decreased CD4+ T cell counts. Levels of inflammatory markers, including
Autor:
Madison Strain, Lanette M Christensen, Jeffrey D. Cirillo, Suat L. G. Cirillo, Preeti Sule, L. Garry Adams, Quinci Plumlee
Publikováno v:
The Journal of Infectious Diseases
BackgroundLegionella can cause Legionnaires’ disease, a potentially fatal form of pneumonia that occurs as sporadic epidemics. Not all strains display the same propensity to cause disease in humans. Because Legionella pneumophila serogroup 1 is res
Autor:
Hien T. Trinh, Daniel A. Powell, M. Lourdes Lewis, Lisa F. Shubitz, Jeffrey A. Frelinger, John N. Galgiani, Marc J. Orbach, Christine D. Butkiewicz
Publikováno v:
J Infect Dis
Murine infections with most Coccidioides spp. strains are lethal by 3 weeks, limiting the study of immune responses. Coccidioides posadasii, strain 1038 (Cp1038), while slowly lethal, resulted in protracted survival of C57BL/6 (B6) mice. In resistant
Autor:
Melissa D. Conrad, Francesca T. Aweeka, Liusheng Huang, Moses R. Kamya, Daniel Mota, Marissa Foster, Meghan Whalen, Grant Dorsey, Philip J. Rosenthal, Patrick K Tumwebaze, Diane V. Havlir, Erika Wallender, Stephen Tukwasibwe, Patience Nayebare, Prasanna Jagannathan, Abel Kakuru, Jennifer Legac
Publikováno v:
The Journal of infectious diseases, vol 216, iss 8
BackgroundIn a recent trial of intermittent preventive treatment in pregnancy (IPTp) in Uganda, dihydroartemisinin-piperaquine (DP) was superior to sulfadoxine-pyrimethamine (SP) in preventing maternal and placental malaria.MethodsWe compared genotyp
Publikováno v:
The Journal of infectious diseases. 218(3)
Background Pneumococci are the major cause of bacterial meningitis globally. To cause meningitis pneumococci interact with the 2 endothelial receptors, polymeric immunoglobulin receptor (pIgR) and platelet endothelial cell adhesion molecule (PECAM-1)
Autor:
Alan Schumitzky, Michael Neely, Steven Fikes, David Brown, Michael VanGuilder, Dodge Baluya, Arnold Louie, Roger W. Jelliffe, Stephanie Kurhanewicz, George L. Drusano, Weiguo Liu, Nichole Robbins
Publikováno v:
The Journal of Infectious Diseases. 211:1326-1333
Background. Meropenem plus levofloxacin treatment was shown to be a promising combination in our in vitro hollow fiber infection model. We strove to validate this finding in a murine Pseudomonas pneumonia model. Methods. A dose-ranging study with mer
Autor:
Sarah Hsieh, Travis B. Nielsen, Jun Yan, Ken Dekitani, Robert A. Bonomo, Thomas A. Russo, Bryan Pascual, Brian Luna, Evgeny Vinogradov, Brad Spellberg, Paul Pantapalangkoor, Kristine M. Hujer, Brandon Yeshoua, Magda Lesczcyniecka, Thomas Schneider, T. Nicholas Domitrovic, Kevin W. Bruhn
Publikováno v:
The Journal of infectious diseases. 216(4)
Background: Extremely drug-resistant (XDR) Acinetobacter baumannii is one of the most commonly encountered, highly resistant pathogens requiring novel therapeutic interventions. Methods: We developed C8, a monoclonal antibody (mAb), by immunizing mic
Autor:
Flavia Luwedde, Veronica Ades, Paul Natureeba, Diane V. Havlir, Albert Plenty, Pius Okong, Julia Mwesigwa, Edwin D. Charlebois, Jane Achan, Tamara D. Clark, Deborah Cohan, Bridget Nzarubara, Moses R. Kamya, Grant Dorsey
Publikováno v:
The Journal of infectious diseases, vol 210, iss 12
Malaria in pregnancy is associated with adverse maternal and neonatal outcomes, such as spontaneous abortions, stillbirth, intrauterine growth restriction, preterm delivery, low birth weight (LBW), maternal anemia, and neonatal death [1]. Human immun
Autor:
Dominique Missiakas, Olaf Schneewind, Peter Verhamme, Thomas Vanassche, Marijke Peetermans, Marc Hoylaerts, Jan Verhaegen, Lucas Van Aelst, Willy Peetermans
Publikováno v:
The Journal of Infectious Diseases. 208:92-100
Staphylococcus aureus (S. aureus) is a frequent cause of catheter-related infections. S. aureus secretes the coagulases staphylocoagulase and von Willebrand factor–binding protein, both of which form a staphylothrombin complex upon binding to proth