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Publikováno v:
J Infect Dis
Swarming motility in Pseudomonas aeruginosa is a multicellular adaptation induced by semisolid medium with amino acids as a nitrogen source. By phenotypic screening, we differentiated swarming from other complex adaptive phenotypes, such as biofilm f
Publikováno v:
J Infect Dis
Intercellular communication and environmental sensing are most often mediated through ligand-receptor binding and signaling. This is true for both host cells and microbial cells. The ligands can be proteins (cytokines, growth factors, and peptides),
Autor:
Araceli Aparecida Hastreiter, Mario Hiroyuki Hirata, Fabrício Moreira Almeida, Maria Regina D'Império Lima, Gislane de Almeida Santos, Elena B. Lasunskaia, José M. Alvarez, Érika Machado de Salles, Eduardo P. Amaral, Caio César Barbosa Bomfim, Rogério Silva do Nascimento, Ricardo Ambrósio Fock, Thatiana Lopes Biá Ventura Simão, Andreza Linhares Rezende, Igor Santiago-Carvalho
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
J Infect Dis
Universidade de São Paulo (USP)
instacron:USP
J Infect Dis
Background The role of myeloid-derived suppressor cells (MDSCs) in patients with severe tuberculosis who suffer from uncontrolled pulmonary inflammation caused by hypervirulent mycobacterial infection remains unclear. Methods This issue was addressed
Autor:
Penghua Wang, Anthony T. Vella, Tao Lin, Andrew G. Harrison, Erol Fikrig, Duomeng Yang, Tingting Geng
Publikováno v:
J Infect Dis
The stimulator of interferon gene (STING) pathway controls both DNA and RNA virus infection. STING is essential for induction of innate immune responses during DNA virus infection, while its mechanism against RNA virus remains largely elusive. We sho
Autor:
Qin Liu, Yuchun Xiao, Xianping Li, Huifang Cao, Liyun Liu, Guangxun Meng, Rong Deng, Wenjie Jin, Zhihong Ren, Liqiong Song, Guy Tran Van Nhieu, Ruiting Lan
Publikováno v:
The Journal of Infectious Diseases. 223:2174-2185
Citrobacter freundii is a significant cause of human infections, responsible for food poisoning, diarrhea, and urinary tract infections. We previously identified a highly cytotoxic and adhesive C. freundii strain CF74 expressing a type VI secretion s
Autor:
Thaisa Lucas Sandri, Miriam Rodi, Benjamin Mordmüller, Andrea Kreidenweiss, Simon Cavallo, Markus Gmeiner, Pierre Blaise Matsiegui, Michael Ramharter, Tamirat Gebru Woldearegai, Gildas B Tazemda-Kuitsouc, David Weber, Sascha Juhas, Luzia Veletzky, Jana Held
Publikováno v:
The Journal of Infectious Diseases. 223:287-296
Mansonella perstans, a filarial nematode, infects large populations in Africa and Latin America. Recently, a potential new species, Mansonella sp “DEUX,” was reported. Carriage of endosymbiotic Wolbachia opens treatment options for Mansonella inf
Autor:
Pankaj Kumar, William A. Petri, Morgan Simpson, Carsten Schwan, Klaus Aktories, Alyse Frisbee
Publikováno v:
The Journal of Infectious Diseases. 225:1296-1300
Clostridioides difficile infection (CDI) represents a significant burden on the health care system, one that is exacerbated by the emergence of binary toxin (CDT)-producing hypervirulent C. difficile strains. Previous work from our laboratory has sho
Autor:
Amber M. Smith, Amanda P. Smith, Jonathan A. McCullers, Peter Vogel, Rhiannon R. Penkert, Julia L. Hurwitz, Eike R. Hrincius
Publikováno v:
J Infect Dis
Background Secondary bacterial coinfections are ranked as a leading cause of hospitalization and morbid conditions associated with influenza. Because vitamin A deficiency (VAD) and insufficiency are frequent in both developed and developing countries
Autor:
Gordon Y. C. Cheung, Michael Otto, Justin S. Bae, Lei He, Govindarajan Rajagopalan, Huiying Lv, Emilie L. Fisher, Min Li, Ryan Liu, Fei Da
Publikováno v:
J Infect Dis
Staphylococcal enterotoxin B (SEB), which is produced by the major human pathogen, Staphylococcus aureus, represents a powerful superantigenic toxin and is considered a bioweapon. However, the contribution of SEB to S. aureus pathogenesis has never b
Autor:
Julia C Cutts, Katherine O’Flaherty, Sophie G Zaloumis, Elizabeth A Ashley, Jo Anne Chan, Marie A Onyamboko, Caterina Fanello, Arjen M Dondorp, Nicholas P Day, Aung Pyae Phyo, Mehul Dhorda, Mallika Imwong, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tran Tinh Hien, Ye Htut, Mayfong Mayxay, M Abdul Faiz, Eizo Takashima, Takafumi Tsuboi, James G Beeson, Francois Nosten, Julie A Simpson, Nicholas J White, Freya J I Fowkes
Publikováno v:
The Journal of infectious diseases, 226(2), 324-331. Oxford University Press
Background Understanding the effect of immunity on Plasmodium falciparum clearance is essential for interpreting therapeutic efficacy studies designed to monitor emergence of artemisinin drug resistance. In low-transmission areas of Southeast Asia, w