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Autor:
Simphiwe Simelane, Harukazu Suzuki, Suraj P. Parihar, Mumin Ozturk, Justin Komguep Nono, Thabo Mpotje, Sugata Roy, Shandre Pillay, Shelby-Sara Jones, Sibongiseni K L Poswayo, Julius Ebua Chia, Frank Brombacher, Reto Guler, Lerato Hlaka
Publikováno v:
The Journal of Infectious Diseases
Background Interleukin 4 (IL-4i1)–induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell acti
Autor:
Walter Basso, Konrad Mühlethaler, Guy Robinson, Jyothi Basapathi Raghavendra, Rachel M. Chalmers, Ines Sarah Dettwiler, Philipp Olias, Zaida Rentería-Solís, Marie-Thérèse Ruf, Sven Poppert, Mireille Meylan, Arwid Daugschies, Karin Troell, Mariko I Dale
Publikováno v:
The Journal of Infectious Diseases. 225:686-695
Background Cryptosporidiosis is a parasitic disease associated with potentially fatal diarrhea. The most used method in Cryptosporidium subtyping is based on the glycoprotein gene gp60. Each infection can represent a parasite population, and it is im
Autor:
Crescentia Cho, Uma M. Nagarajan, Ian Huntress, Hayden N. Brochu, Erin Harrell, J. Ashley Ezzell, Shanmugam Nagarajan, Clare E. Gyorke, Xinxia Peng
Publikováno v:
J Infect Dis
Chlamydia trachomatis-genital infection in women can be modeled in mice using Chlamydia muridarum. Using this model, it has been shown that the cytokines tumor necrosis factor (TNF)α and interleukin (IL)-1α lead to irreversible tissue damage in the
Publikováno v:
J Infect Dis
Pertussis, caused by Bordetella pertussis, is a reemerging disease that can produce severe disease manifestations in infants, including pulmonary hypertension (PH). B. pertussis-induced PH is a major risk factor for infection-induced death, but the m
Autor:
Mélanie Foulon, Marie Robbe-Saule, Lucille Esnault, Marine Malloci, Anthony Mery, Jean-Paul Saint-André, Anne Croue, Marie Kempf, Chadi Homedan, Estelle Marion, Laurent Marsollier
Publikováno v:
The Journal of Infectious Diseases. 224:1973-1983
Ketogenic diets have been used to treat diverse conditions, and there is growing evidence of their benefits for tissue repair and in inflammatory disease treatment. However, their role in infectious diseases has been little studied. Buruli ulcer (Myc
Autor:
Pierre Carnevale, Sylvie Manguin
Publikováno v:
The Journal of Infectious Diseases
Residual malaria transmission is the actual maintained inoculation of Plasmodium, in spite of a well-designed and implemented vector control programs, and is of great concern for malaria elimination. Residual malaria transmission occurs under several
Autor:
Timoléon Tchuinkam, Martin K. Rono, Parfait Awono-Ambene, Alice Kamau, Argaw Ambelu, Prophet Ingosi, Joseph M. Mwangangi, Edmond Kopya, Delenasaw Yewhalaw, Teshome Degefa, Roland Bamou, Flobert Njiokou, Christophe Antonio Nkondjio, Kora Tushune, Charles Mbogo, Zewdie Birhanu, Janet Midega
Publikováno v:
The Journal of Infectious Diseases
Introduction In order to improve our understanding of the fundamental limits of core interventions and guide efforts based on prioritization and identification of effective/novel interventions with great potentials to interrupt persistent malaria tra
Autor:
Manuel W Hetzel, Justin Pulford, Michelle Katusele, Leanne J. Robinson, Daniela Rodriguez-Rodriguez, Alma Auwun, Moses Laman, Magdalene Marem
Publikováno v:
The Journal of Infectious Diseases
Background Malaria transmission is currently resurging in Papua New Guinea (PNG). In addition to intervention coverage, social and cultural factors influence changes in epidemiology of malaria in PNG. This study aimed to better understand the role of
Autor:
Jolaine M Wilson, Germie van den Dobbelsteen, Rita Chan, Anthony Romanello, Victor J. Torres, Craig McLahan, Danielle Malone, Matthew Willms, Alessandra Buoninfante, Jeffrey Fernandez, Holly Sanders, Jan Poolman, Jessica Henn, Ashley L. DuMont, Kaitlyn Grubb
Publikováno v:
The Journal of Infectious Diseases. 225:1460-1470
Vaccines against Staphylococcus aureus have eluded researchers for >3 decades while the burden of staphylococcal diseases has increased. Early vaccine attempts mainly used rodents to characterize preclinical efficacy, and all subsequently failed in h
Autor:
Manabu Fujimoto, Hiroyuki Matsue, Hideaki Miyachi, Hanako Koguchi-Yoshioka, Yuumi Nakamura, Takashi Sugihira, Shinobu Saijo, Reika Aoyama, Seiichiro Wakabayashi, Gabriel Núñez
Publikováno v:
The Journal of Infectious Diseases. 223:1753-1765
Background Among skin commensal fungi, lipophilic Malassezia species exist on nearly all human skin surfaces. The pathophysiology of Malassezia-associated skin diseases remains poorly understood due in part to the lack of appropriate animal models. O