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of 57
pro vyhledávání: ''
Autor:
Ambrish Jha, Dominique M. Dockery, Dipak Kumar Raj, Aisha S Obeidallah, Ian C. Michelow, Bonnie Colantuono, Jonathan D. Kurtis, Patrick E. Duffy, Sangshin Park, Christina E. Nixon, Christian P. Nixon, Rayna A Silva-Viera
Publikováno v:
The Journal of Infectious Diseases. 218:1792-1801
BACKGROUND: Antigametocyte-specific immune responses may regulate Plasmodium falciparum gametocyte density, providing the rationale for pursuing transmission-blocking vaccines (TBVs) that target gametocytes in the human host. METHODS: To identify nov
Autor:
Harparkash Kaur, Robert W. Sauerwein, Chris Drakeley, Seif Shekalaghe, Lucy C Okell, Arnold Ndaro, Collins K. Mweresa, Teun Bousema, Khalid B. Beshir, Colin J. Sutherland, Patrick Sawa, Sabah A. Omar, Henk D. F. H. Schallig, Jaffu Chilongola, Rachel Hallett
Publikováno v:
The Journal of Infectious Diseases
Journal of infectious diseases, 208(12), 2017-2024. Oxford University Press
The Journal of Infectious Diseases, 208, 2017-24
Journal of Infectious Diseases; Vol 208
The Journal of Infectious Diseases, 208, 12, pp. 2017-24
Journal of infectious diseases, 208(12), 2017-2024. Oxford University Press
The Journal of Infectious Diseases, 208, 2017-24
Journal of Infectious Diseases; Vol 208
The Journal of Infectious Diseases, 208, 12, pp. 2017-24
BACKGROUND: Parasite clearance time after artemisinin-based combination therapy (ACT) may be increasing in Asian and African settings. The association between parasite clearance following ACT and transmissibility is currently unknown. METHODS: We det
Autor:
Ling Cheng, Stephen T. McGarvey, Mario Jiz, Valeria Fabre, Jennifer F. Friedman, Luz P. Acosta, Eric S. White, Sunthorn Pond-Tor, Hannah M. Coutinho, Hai-Wei Wu, Remigio M. Olveda, Jonathan D. Kurtis, Blanca R. Jarilla
Publikováno v:
The Journal of Infectious Diseases. 203:707-714
Background. Schistosomes infect 200 million individuals annually and cause significant hepatic fibrosis in up to 20%. Little is known regarding the mechanisms of schistosome-associated hepatic fibrosis in humans, and few biomarkers for risk of fibros
Autor:
Fraction K. Dzinjalamala, O. Colin Stine, Christopher V. Plowe, Shannon Takala-Harrison, Miriam K. Laufer, Terrie E. Taylor
Publikováno v:
The Journal of Infectious Diseases. 202:801-808
The spread of drug-resistant Plasmodium falciparum malaria has been a major impediment to malaria control and threatens prospects for elimination. We recently demonstrated the return of chloroquine-susceptible malaria in Malawi after chloroquine use
Autor:
Sam Dunyo, Chris Drakeley, Rachel Hallett, Rosalynn Ord, Neal Alexander, Musa Jawara, Geoffrey A. T. Targett, Colin J. Sutherland
Publikováno v:
The Journal of Infectious Diseases. 196:1613-1619
Background. Observations in natural Plasmodium falciparum populations after removal of failing drugs suggest that there is a fitness cost of drug resistance.Methods. To examine the effect of transient removal of drug pressure, we analyzed seasonal ch
Autor:
Anders Enevold, Anja T. R. Jensen, Michael Alifrangis, Trine Staalsoe, Thor G. Theander, David C. Warhurst, Martha M. Lemnge, Anita M. Rønn, Insaf F. Khalil, John Lusingu, Lasse S Vestergaard, Ib C. Bygbjerg, Michael B. Dalgaard
Publikováno v:
The Journal of Infectious Diseases. 193:1738-1741
Two main haplotypes, CVIET and SVMNT, of the Plasmodium falciparum chloroquine-resistance transporter gene (Pfcrt) are linked to 4-aminoquinoline resistance. The CVIET haplotype has been reported in most malaria-endemic regions, whereas the SVMNT hap
Autor:
Francisca Mutapi, Takafira Mduluza, Yvonne Harcus, Richard Burchmore, Nicholas Midzi, Rick M. Maizels, Aude Foucher, Gavin Nicoll, C. Michael R. Turner
Publikováno v:
The Journal of Infectious Diseases. 192:1108-1118
Background Schistosomiasis is a major parasitic disease affecting >200 million people in the developing world, and 400 million people are at risk for infection. This study aimed to identify and compare proteins recognized by serum samples from schist
Autor:
J. Teun Bousema, Margaret Pinder, Rosalynn Ord, Emilia Osman, Colin J. Sutherland, Maarten van Niekerk, Larissa Meerman, Rachel Hallett, Gijs Walraven
Publikováno v:
The Journal of Infectious Diseases, 192, 1651-7
The Journal of Infectious Diseases, 192, 9, pp. 1651-7
The Journal of Infectious Diseases, 192, 9, pp. 1651-7
Contains fulltext : 48037.pdf (Publisher’s version ) (Closed access) Two hundred thirty-four Gambian children with severe falciparum malaria who were admitted to the pediatric ward of a rural district hospital each were matched for age with a same-
Autor:
Martin Hoyle, Richard K. Grencis, J. Kamgno, Jerzy M. Behnke, Helen Faulkner, Janette E. Bradley, Joseph D. Turner, Lawrence Rentoul, Michel Boussinesq, Kathryn J. Else, Joseph A. Jackson
Publikováno v:
The Journal of Infectious Diseases. 190:1804-1811
Some humans are persistently more susceptible to gastrointestinal nematodes than others. Here, for the first time, susceptibility to reinfection has been linked to host cytokine responses. Ascaris lumbricoides and Trichuris trichiura abundance was as
Autor:
Gachuhi Kimani, John H. Ouma, Frances M. Jones, Narcis B. Kabatereine, Anthony J. C. Fulford, Timothy Kamau, Edridah M. Tukahebwa, David W. Dunne, Francis Kazibwe, Joseph K. Mwatha, H. C. Kariuki, Birgitte J. Vennervald, Klaudia Walter, Sarah Joseph
Publikováno v:
The Journal of Infectious Diseases. 190:835-842
Levels of Schistosoma mansoni-induced interleukin (IL)-4 and IL-5 and posttreatment levels of immunoglobulin E recognizing the parasite's tegument (Teg) correlate with human resistance to subsequent reinfection after treatment. We measured changes in