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Publikováno v:
The Journal of Infectious Diseases. 208:211-217
Background. Klebsiella pneumoniae liver abscess (KPLA) is prevalent in East Asia. Use of amoxicillin/ampicillin may lead to overgrowth of K. pneumoniae in the intestine and predispose to KPLA. We used an animal study and nationwide population-based d
Autor:
Alimuddin Zumla, Juraj Ivanyi
Publikováno v:
The Journal of Infectious Diseases. 208:185-188
from failures in drug supply and from drug intolerance. Shortening of the tuberculosis treatment period for both drugsusceptible and drug-resistant tuberculosis would greatly improve tuberculosis management and infection control. Immunotherapy has be
Publikováno v:
The Journal of Infectious Diseases. 207:319-322
Chikungunya virus (CHIKV) is an alphavirus prevalent in tropical regions. It causes an acute febrile disease that, in elderly individuals and newborns, is often associated with severe complications. We previously reported the isolation and characteri
Autor:
Guiyun Li, David W. Scheifele, Marc Dionne, Suzana Sabaiduc, Nathalie Bastien, Naveed Z. Janjua, Martin Petric, Jennifer L. Gardy, Vladimir Gilca, Guy Boivin, Gaston De Serres, Yan Li, Danuta M. Skowronski, Dale Purych
Publikováno v:
The Journal of Infectious Diseases. 206:1852-1861
Background. Cases of infection due to a novel swine-origin variant of influenza A virus subtype H3N2 (H3N2v) have recently been identified in the United States, primarily among children. We estimate levels of cross-reactive antibody to H3N2v by age a
Autor:
Yuemei Hu, Qunying Mao, Yun-Tao Zhang, Kai Chu, Yuxiao Wang, Fengcai Zhu, Xiu-Ling Li, Pei Liu, Jingxin Li, Shiyuan Wang, Nianmin Shi, Fan-Yue Meng, Mingwei Wei, Zhenglun Liang, Hong Tao
Publikováno v:
The Journal of infectious diseases. 215(1)
BACKGROUND This study evaluated the 2-year efficacy, immunogenicity, and safety of the Vigoo enterovirus 71 (EV71) vaccine. METHOD In an initial phase 3 study, we randomly assigned healthy infants and children aged 6-35 months (ratio, 1:1) to receive
Publikováno v:
The Journal of infectious diseases. 216(5)
Background The need for an effective vaccine against human tuberculosis has driven the development of different candidates and vaccination strategies. Novel live attenuated vaccines are being developed that promise greater safety and efficacy than BC
Autor:
Walid Heneine, J. Gerardo García-Lerma, Adrian S. Ray, James Mitchell, Ivana Massud, James F. Rooney, Darius Babusis, Michael D. Miller, Frank Deyounks
Publikováno v:
The Journal of infectious diseases. 214(7)
Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir that efficiently delivers tenofovir diphosphate to lymphoid cells following oral administration. We investigated whether the combination of TAF and emtricitabine (FTC) could prevent simian/h
Publikováno v:
J Infect Dis
The emergence of drug-resistant malaria highlights the need for new agents. A desired characteristic of candidate antimalarials is rapid killing of parasites. This is typically measured by the rate of exponential clearance of parasitemia following tr
Autor:
John A. Lednicky, Tao Wang, Gregory C. Gray, Meng-Meng Ma, Mai-Juan Ma, Yao Xia, Benjamin Anderson, Bo Shu, Jiahai Lu
Publikováno v:
The Journal of infectious diseases. 214(4)
BACKGROUND Modern agricultural practices create environmental conditions conducive to the emergence of novel pathogens. Current surveillance efforts to assess the burden of emerging pathogens in animal production facilities in China are sparse. In Gu
Publikováno v:
The Journal of Infectious Diseases. 205:1173-1177
Iron restriction has been proposed as a cause of erythropoietic suppression in malarial anemia; however, the role of iron in malaria remains controversial, because it may increase parasitemia. To investigate the role of iron-restricted erythropoiesis