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Autor:
Thomas B. Nutman, Michael P. Fay, Gokul Raj Kathamuthu, Vaithilingam V. Banurekha, Subash Babu, Nathella Pavan Kumar, Kadar Moideen, Dina Nair
Publikováno v:
J Infect Dis
BackgroundHelminths and tuberculosis (TB) largely overlap at the population level. Whether helminth infections influence disease severity and bacterial burdens in TB is not well understood.MethodsThis study was conducted to examine the disease severi
Autor:
Zhi-Hua Jiang, Men-Bao Qian, Hualei Xin, Simon I. Hay, Yichao Yang, Zhongjie Li, Shi-Zhu Li, Yu Chen, Ying-Dan Chen, Junling Sun, Zhuoxin Huang, Jianxing Yu
Publikováno v:
The Journal of infectious diseases. 225(3)
Background To understand Clonorchis sinensis reinfection and the determinants of reinfection in endemic areas is important in establishment of control measures. Methods A prospective cohort study was implemented in Hengxian County, Guangxi, China. In
Publikováno v:
The Journal of infectious diseases. 225(8)
In Southeast Asia, mutations in the Plasmodium falciparum K13 gene have led to delayed parasite clearance and treatment failures in patients with malaria receiving artemisinin combination therapies. Until recently, relevant K13 mutations had been mos
Autor:
Christopher D. Huston, Damon M. Osbourn, David W. Griggs, Sangun Lee, Don Girouard, Gillian Beamer, Saul Tzipori, Melanie Ginese
Publikováno v:
J Infect Dis
Background Cryptosporidiosis, an enteric protozoon, causes substantial morbidity and mortality associated with diarrhea in children 75% of diarrhea reported in these children. Methods Gnotobiotic piglets were orally challenged with C hominis oocysts,
Autor:
Nguyen Thi Han Ny, Nguyen Thuy Thuong Thuong, Dang Thi Hong Mui, Vu Thi Thu Van, Nguyen Thi Thu Hiep, Le Van Tan, Nguyen Ho Hong Hanh, Guy E. Thwaites, Joseph Donovan, Ho Dang Trung Nghia, Nguyen Hoan Phu, Trinh T. B. Tram
Publikováno v:
The Journal of infectious diseases. 225(9)
Background Helminth infections may modulate the inflammatory response to Mycobacterium tuberculosis and influence disease presentation and outcome. Strongyloides stercoralis is common among populations with high tuberculosis prevalence. Our aim was t
Autor:
James J Sola, Perry D Wiseman, Joseph Henry, Jay Wells, Joshua L. Moore, Christopher W. Schellhase, Xiankun Zeng, Jeremy J Bearss, Kelly S. Stuthman, Luis A. Lugo-Roman, Jennifer Kalapaca, Darrel Wetzel, Elliot Ramos-Rivera, Annie Madar, William D. Pratt, Veronica Soloveva, Ginger Donnelly, Lydia G Downey, Tami Unangst, Nicole L. Garza, Adele Miller, Jesse T. Steffens, Janice A. Williams, Anthony P. Cardile, Mark G. Kortepeter, Paul W Blair, Isaac L Downs, Mark A. Chappell, Ronald B. Reisler, Franco Rossi, Shannon T Marko, Christian Hofer, Jimmy O. Fiallos, Sean A. Vantongeren, Eugene Blue, Cristian Madar, Karen A. Martins, Sina Bavari
Publikováno v:
J Infect Dis
BackgroundEbola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated the effect of EVD supportive care algorithms on duration of survival in a controlled nonhuman primate (
Autor:
Ousmane A. Koita, Donald J. Krogstad
Publikováno v:
The Journal of infectious diseases. 217(5)
Autor:
Enny Kenangalem, Emiliana Tjitra, Ric N. Price, Daniel A. Lampah, Tsin W. Yeo, Nicholas M. Anstey
Publikováno v:
The Journal of Infectious Diseases. 208:813-817
Heme oxygenase 1 expression is increased in pediatric patients with malaria. The carboxyhemoglobin level (a measure of heme oxygenase 1 activity) has not been assessed in adult patients with malaria. Results of pulse co-oximetry revealed that the mea
Publikováno v:
The Journal of Infectious Diseases. 208:211-217
Background. Klebsiella pneumoniae liver abscess (KPLA) is prevalent in East Asia. Use of amoxicillin/ampicillin may lead to overgrowth of K. pneumoniae in the intestine and predispose to KPLA. We used an animal study and nationwide population-based d
Autor:
Yuemei Hu, Qunying Mao, Yun-Tao Zhang, Kai Chu, Yuxiao Wang, Fengcai Zhu, Xiu-Ling Li, Pei Liu, Jingxin Li, Shiyuan Wang, Nianmin Shi, Fan-Yue Meng, Mingwei Wei, Zhenglun Liang, Hong Tao
Publikováno v:
The Journal of infectious diseases. 215(1)
BACKGROUND This study evaluated the 2-year efficacy, immunogenicity, and safety of the Vigoo enterovirus 71 (EV71) vaccine. METHOD In an initial phase 3 study, we randomly assigned healthy infants and children aged 6-35 months (ratio, 1:1) to receive