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Autor:
Ebony Williams, Ashley Gilmore, Michael S. Saag, Edgar T. Overton, Ricardo A. Franco, Nichole Bruner, Anthony B Lee, Sandra Karumberia
Publikováno v:
The Journal of Infectious Diseases. 222:S365-S375
BackgroundThe effectiveness of hepatitis C testing and linkage-to-care (LTC) is poorly characterized in low-resource jurisdictions facing gaps in harm reduction, including illegality of syringe exchange services. Effectiveness of a community-based te
Autor:
Rajesh T. Gandhi, Justin Ritz, Laura M. Smeaton, Joseph J. Eron, Adriana Andrade, Evelyn Hogg, Vincent Vu, Karen T. Tashima, Carl J. Fichtenbaum
Publikováno v:
J Infect Dis
Background Short-term (48-week) results of the OPTIONS trial showed that nucleoside reverse transcriptase inhibitors (NRTIs) can be safely omitted from salvage therapy as long as the regimen has a cumulative activity of >2 active antiretroviral medic
Autor:
Julia Aepfelbacher, Julia B Balmaceda, Kirsten Zambell, Karyn Hawkins, Colleen Hadigan, Aviva S. Mattingly, Kara Anne Curl, Julia B. Purdy, Nicola Dee, Cheryl Chairez
Publikováno v:
J Infect Dis
Little is known about the effects of lifelong human immunodeficiency virus (HIV) or antiretroviral therapy on hepatic steatosis and fibrosis. Using transient elastography, we evaluated 46 young adults with lifelong HIV and 20 matched HIV-negative con
Publikováno v:
The Journal of Infectious Diseases. 219:851-855
We propose an outcome indicator, the percentage of newly diagnosed persons achieving viral suppression within 3 months of diagnosis, to be included in the US National HIV/AIDS Strategy to monitor the progress in human immunodeficiency virus (HIV) car
Autor:
Cynthia Firnhaber, Jared M. Baeten, Deborah Donnell, Mina C. Hosseinipour, Cynthia Riviere, Connie Celum, Mulinda Nyirenda, Jorge Sanchez, Thomas B. Campbell, N. Kumarasamy, James Hakim, Actg Pearls, Khuanchai Supparatpinyo, Aspire Study Team, Breno Santos, Anne Cent, Rhoda Ashley Morrow, Beatriz Grinsztejn, Umesh G. Lalloo, Ting Hong
Publikováno v:
The Journal of Infectious Diseases. 215:907-910
Objective Tenofovir disoproxyl fumarate (TDF) disoproxyl fumarate (TDF) has in vitro activity against herpes simplex virus type 2 (HSV-2) and reduced HSV-2 acquisition as preexposure prophylaxis. Whether TDF-containing antiretroviral therapy (ART) re
Autor:
Mark, Gompels, David T, Dunn, Andrew, Phillips, Debbie, Dooley, Andrew, De Burgh Thomas, Jane, Anderson, Frank, Post, Deenan, Pillay, Brian, Gazzard, Teresa, Hill, Margaret, Johnson, Richard, Gilson, Loveleen, Bansi, Philippa, Easterbrook, Martin, Fisher, John, Walsh, Chloe, Orkin, Jonathan, Ainsworth, Clifford, Leen, Caroline, Sabin, Sundhiya, Mandalia
Publikováno v:
The Journal of Infectious Diseases. 205:540-547
INTRODUCTION The CD4 count and CD4 percentage (CD4%) are both strong predictors of clinical disease progression in human immunodeficiency virus (HIV). Although individuals may show discordancy between their CD4 count and CD4%, the clinical relevance
Autor:
Camille E. Puronen, Richard M. Novak, Martyn A. French, Adam Rupert, James D. Neaton, Paul R. Bohjanen, Irini Sereti, David R. Boulware, Katherine Huppler Hullsiek, Jason V. Baker
Publikováno v:
The Journal of Infectious Diseases. 203:1637-1646
Antiretroviral therapy (ART) has substantially reduced morbidity and mortality in human immunodeficiency virus (HIV)-infected persons [1–4]. Yet even with adequate HIV virologic suppression, substantial morbidity and mortality still occurs during t
Autor:
Kristine B. Patterson, Stephanie Malone, Angela D. M. Kashuba, Melissa Spacek, Paris Heidt, Heather M.A. Prince, Kevin C. Brown, Myron S. Cohen, Julie B. Dumond, Nicholas J. Shaheen
Publikováno v:
The Journal of Infectious Diseases. 203:1484-1490
Between 2004 and 2007, the incidence of HIV/AIDS increased 15% in the United States [1]. In men who have sex with men (MSM), this increase was 26%. The highest risk of HIV acquisition occurs with receptive anal intercourse [2], as the rectal mucosa i
Autor:
Logan Reddy, Devan Govender, Tonya M. Esterhuizen, Dhayendre Moodley, Linda Ngaleka, Pravi Moodley, Bipraj Singh
Publikováno v:
The Journal of Infectious Diseases. 203:1231-1234
We described HIV incidence and mother-to-child transmission (MTCT) among women during pregnancy and lactation. Forty-eight (3.4%) of 1396 women seroconverted during pregnancy or
Autor:
L, Conley, T, Bush, T M, Darragh, J M, Palefsky, E R, Unger, P, Patel, E M, Kojic, S, Cu-Uvin, H, Martin, E T, Overton, J, Hammer, K, Henry, C, Vellozzi, K, Wood, J T, Brooks, Kenneth, Griffie
Publikováno v:
The Journal of Infectious Diseases. 202:1567-1576
Background. The prevalence of and risk factors for abnormal anal cytology among men and women with human immunodeficiency virus (HIV) infection have not been extensively investigated.Methods. The Study to Understand the Natural History of HIV and AID