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pro vyhledávání: '"Steven Highfill"'
Publikováno v:
The Journal of Immunology. 192:205.11-205.11
Genetically engineered T-cells expressing chimeric antigen receptors directly target cell surface antigens on tumor cells. CARs have shown remarkable activity in clinical trials for hematologic malignancies but remain unproven for the treatment of so
Autor:
Jaime Modiano, Sarah Highfill, Qing Zhou, Mitzi Lewellen, Steven Highfill, Christoph Bucher, Bruce Blazar
Publikováno v:
The Journal of Immunology. 184:49.17-49.17
In addition to its effect to limit the number of cell division cycles and the accumulation of memory T cells, recent data suggest NFATc2 may be required to enable development and function of regulatory T cells (Tregs). Here, we verified loss of NFATc