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Autor:
Mary A. Elrick, Vincent I. Poon, Jillian M. Brandon, Luke R. K. Hughson, Ninan Abraham, Katelin N. Townsend, Izabelle Gadawski, Julian J. Lum, E. John Wherry, Sarah MacPherson, Katrin Schlie, Lindsay DeVorkin, Hélène C. F. Côté, Ashley Westerback, Noboru Mizushima
Publikováno v:
The Journal of Immunology. 194:4277-4286
The activation and expansion of effector CD8+ T cells are essential for controlling viral infections and tumor surveillance. During an immune response, T cells encounter extrinsic and intrinsic factors, including oxidative stress, nutrient availabili