Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Samuel Huber"'
Autor:
Lisa Charlotte Heinig, Emily Valentina Madelaine Huth, Karsten Yan, Neele Schumacher, Mikolaj Nawrocki, Niels Christian Lory, Peter Bradtke, Tabea Bertram, Guido Rattay, Joanna Schmid, Samuel Huber, Thorsten Wiech, Dirk Schmidt-Arras, Stefan Rose-John, Hans-Willi Mittrücker
Publikováno v:
The Journal of Immunology. 210:1717-1727
IL-6 plays a fundamental role in T cell differentiation and is strictly controlled by surface expression and shedding of IL-6R. IL-6 also acts on other cells that might affect T cell maturation. To study the impact of cell-autonomous and uncontrolled
Autor:
Zeinab Abdullah, Francis J. Huber, Nicola Gagliani, Friederike Stuhlmann, Franziska Mathies, Samuel Huber, Christoph Schramm, M. Luetgehetmann, Oliver Seiz, Urmi Roy, Tanja Bedke, Richard A. Flavell, Thomas Meyer, Till Strowig, Christian Krebs, Doerte Kleinschmidt, Johannes Herkel, Ulf Panzer, Niklas Steffens, Mareike von Petersdorff
Publikováno v:
The Journal of Immunology. 201:3558-3568
Inflammatory bowel disease is associated with extraintestinal diseases such as primary sclerosing cholangitis in the liver. Interestingly, it is known that an imbalance between Foxp3+ regulatory T cells (Treg) and Th17 cells is involved in inflammato
Autor:
Babett Steglich, Jill Noll, Philipp Huber, Anastasios D. Giannou, Ahmad Mustafa Shiri, Thomas Ernst, Peter Hübener, Richard A. Flavell, Dörte Kleinschmidt, Eithan Galun, Jan Kempski, Tobias A. Fuchs, Samuel Huber, Tanja Bedke, Francis J. Huber, Nicola Gagliani, Heather M. McGee, Elena Tasika, Claudia Wegscheid, Ansgar W. Lohse, Theodora Agalioti, Hannelore Lotter, Jonathan H. Axelrod, Gisa Tiegs, Niklas Steffens
Publikováno v:
The Journal of Immunology. 199:4078-4090
Acute liver injury can be secondary to a variety of causes, including infections, intoxication, and ischemia. All of these insults induce hepatocyte death and subsequent inflammation, which can make acute liver injury a life-threatening event. IL-22
Autor:
Jan-Eric Turner, Brigitta Stockinger, Oliver M. Steinmetz, Sonja Kapffer, Rolf A.K. Stahl, Hans-Joachim Paust, Ulf Panzer, Richard A. Flavell, Samuel Huber, Friederike Ufer, Sonja Krohn, Christian Krebs, Manuel A. Friese, Tobias Koyro
Publikováno v:
The Journal of Immunology. 197:449-457
The ability of CD4+ T cells to differentiate into pathogenic Th1 and Th17 or protective T regulatory cells plays a pivotal role in the pathogenesis of autoimmune diseases. Recent data suggest that CD4+ T cell subsets display a considerable plasticity
Autor:
Alexander Quaas, Manfred Blessing, Christoph Schramm, Ansgar W. Lohse, Dorothee Schwinge, Susetta Finotto, Michael Wegmann, Joachim Maxeiner, Katrin Presser, Steffen Schmitt, Samuel Huber
Publikováno v:
Scopus-Elsevier
In allergic airway disease, Treg may play an important role in the modulation of airway hyperreactivity (AHR) and inflammation. We therefore investigated the therapeutic potential of Treg in an Ag-dependent murine asthma model. We here describe that
Autor:
Steffen Schmitt, Manfred Blessing, Christoph Schramm, Peter R. Galle, Christoph Becker, Markus F. Neurath, Martina Protschka, Hans A. Lehr, Samuel Huber, Amrit Mann
Publikováno v:
The Journal of Immunology. 173:6526-6531
Data regarding the role of TGF-β for the in vivo function of regulatory CD4+CD25+ T cells (Treg) are controversial. A transgenic mouse model with impaired TGF-β signaling specifically in T cells was used to assess the role of endogenous TGF-β for
Autor:
Laura Garcia Perez, Thomas Korn, Caspar Ohnmacht, Samuel Huber, Doron Merkler, Anne Krug, Mario Kreutzfeldt, Maria Potthast, Christopher Sie
Publikováno v:
J. Immunol. 203, 1417-1427 (2019)
The Journal of Immunology
Journal of Immunology (2019)
The Journal of Immunology
Journal of Immunology (2019)
Homing of pathogenic CD4+ T cells to the CNS is dependent on α4 integrins. However, it is uncertain whether α4 integrins are also required for the migration of dendritic cell (DC) subsets, which sample Ags from nonlymphoid tissues to present it to