Zobrazeno 1 - 3
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pro vyhledávání: '"Elizabeth M. Jaffee"'
Publikováno v:
The Journal of Immunology. 210:859-868
Advances in cancer immunotherapy, particularly immune checkpoint inhibitors, have dramatically improved the prognosis for patients with metastatic melanoma and other previously incurable cancers. However, patients with pancreatic ductal adenocarcinom
Autor:
Brian H. Ladle, Satoshi Murata, Eric R. Lutz, Matthew E. Wolpoe, Peter S. Kim, Holly M. Smith, Todd D. Armstrong, Leisha A. Emens, R. Todd Reilly, Elizabeth M. Jaffee, Susan E. Ivie
Publikováno v:
The Journal of Immunology. 176:974-983
T cell costimulation via OX40 is known to increase CD4+ T cell expansion and effector function and enhances the development of T cell memory. OX40 costimulation can also prevent, and even reverse, CD4+ T cell anergy. However, the role of OX40 in CD8+
Autor:
Elizabeth M. Jaffee, Anne M. Ercolini, Yi-Cheng Chen, Martin Giedlen, R. Todd Reilly, Jean-Pascal Machiels, Jill E. Slansky
Publikováno v:
The Journal of Immunology. 170:4273-4280
The HER-2/neu (neu-N)-transgenic mice are a clinically relevant model of breast cancer. They are derived from the parental FVB/N mouse strain and are transgenic for the rat form of the proto-oncogene HER-2/neu (neu). In this study, we report the iden